西北農林科技大學“青年英才計畫”優秀青年人才獲得者，副教授，碩士生導師。
基本介紹
- 中文名：陳華濤
- 國籍：中國
- 民族：漢族
- 出生地：安徽碭山
- 出生日期：1984年6月
- 職業：副教授、碩士生導師
- 性別：男
個人簡介,成就榮譽,代表性論文,
個人簡介
一、教育及工作經歷
2015年12月入職西北農林科技大學動物醫學院並被直聘為副教授、碩士生導師
2013年10月至2015年9月 獲日本學術振興會（JSPS）外國人特別研究員職位，在日本京都大學藥學研究科系統生物學研究室從事博士後工作，合作導師為世界著名生物鐘研究科學家岡村均教授
2013年9月畢業於日本九州大學生物資源環境科學府資源生物科學（動物生殖生理學）專業，獲農學博士學位，導師為服部真彰教授
2010年6月畢業於西北農林科技大學動物醫學院臨床獸醫學專業，獲農學碩士學位，導師為靳亞平教授
2007年7月畢業於西北農林科技大學動物科技學院動物醫學專業，獲農學學士學位，導師為宋曉平教授
二、研究方向及開設課程
研究方向：（1）獸醫產科學基礎；（2）哺乳動物生殖生物鐘生理學功能研究；（3）哺乳動物生物鐘調控脂類、糖類代謝機制研究。
開設課程：《獸醫產科學》、《動物生殖內分泌》、《動物生物學專題》、《獸醫生物技術進展》。
三、 主持的科研項目
1.國家自然科學基金面上項目（2018/01-2021/12）：肝臟生物鐘通過USP2-45/PPARα信號通路調控肝臟甘油三酯含量的機制研究，主持人。
2.國家自然科學基金青年基金項目（2017/01-2019/12）：BMAL1基因介導的山羊睪丸間質細胞生物鐘調控睪酮合成的分子機制研究；主持人。
3.中國博士後科學基金特別資助（2018/06-2019/12），主持人。
4.中國博士後科學基金一等資助（2017/06-2019/06），主持人。
5.陝西省2018年博士後配套資助，主持人。
6.陝西省博士後科研資助項目，主持人。
7.西北農林科技大學引進人才科研啟動專項（2016/01-2020/12）：哺乳動物生殖生物鐘調控機制及功能研究，主持人。
8.陝西省引進人才專項配套經費（2017/06-2020/05）， 主持人。
9.中央高校科研業務基本費（2017/05-2020/04），主持人。
四、 學術兼職
美國生理學學學會正會員；中國畜牧獸醫學會高級會員；中國細胞生物學學會生物節律分會會員。
成就榮譽
2015年入選西北農林科技大學“青年英才計畫”優秀青年人才
2013年榮獲日本學術振興會JSPS外國人特別研究員職位
2010年榮獲國家留學基金委建設高水平大學公派研究生項目獎學金
代表性論文
近年來，以第一作者、通訊作者及共同作者在《NatureCommunications》、《Journal of Biological Chemistry》、《CellularSignalling》、《American Journal of Physiology-Endocrinology and Metabolism》、《American Journal of Physiology-Cell Physiology》、《Chronobiology International》、《Biologyof Reproduction》、《FEBSJournal》、《Journal ofCellularPhysiology》、《Frontiers in Endocrinology》、《Biochemical and Biophysical Research Communications》、《Theriogenology》、《Journal of reproduction and Development》等國內外期刊上發表學術論文30餘篇。
ChenHuatao,GaoLei, Yang Dan, Xiao Yaoyao, Zhang Manhui, Li Cuimei, Wang Aihua, Jin Yaping, Coordination between the circadian clock and androgen signaling is required to sustain rhythmic expression of Elovl3 in mouse liver [J]. Journal of Biological Chemistry, 2019.
Gao Lei, Chen Huatao, Li Cuimei, Xiao Yaoyao, Yang Dan, Zhang Manhui, Zhou Dong, Liu Wei, Wang Aihua, Jin Yaping, ER stress activation impairs the expression of circadian clock and clock-controlled genes in NIH3T3 cells via an ATF4-dependent mechanism [J]. Cellular Signalling, 57: 89-101, 2019.
WangLei, Lu Minjie, Zhang Ruixue, Guo Wenwen, Lin Pengfei, Yang Diqi, Chen Huatao, Tang Keqiong, Zhou Dong, Wang Aihua, Jin Yaping, Inhibition of Luman/CREB3 expression leads to the upregulation of testosterone synthesis in mouse Leydig cells [J]. Journal of Cellular Physiology, 2019.
Yang Diqi, Jiang Tingting, Liu Jianguo, Hong Jin, Lin Pengfei,Chen Huatao, Zhou Dong, Tang Keqiong, Wang Aihua, Jin Yaping, Interferon-τ regulates prostaglandin release in goat endometrial stromal cells via JAB1-unfolded protein response pathway [J]. Theriogenology , 113: 237-246, 2018.
YangDiqi, Jiang Tingting, Liu Jianguo, Zhang Beibei, Lin Pengfei,Chen Huatao, Zhou Dong, Tang Keqiong, Wang Aihua, Jin Yaping, CREB3 regulatory factor – mTOR – autophagy regulates goat endometrial function during early pregnancy [J]. Biology of Reproduction, 98(5): 713-721, 2018.
ChaoHsu-wen, Doi Masao, Fustin Jean-Michel, Chen Huatao, Murase Kimihiko, Maeda Yuki, Hayashi Hida, Tanaka Rina, Sugawa Maho, Mizuguchi Naoki, Yamaguchi Yoshiaki, Yasunaga Jun-ichirou, Matsuoka Masao, Sakai Mashito, Matsumoto Michihiro, HamadaShinshichi, Okamura Hitoshi, Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway [J].Nature Communications, 8(1): 2238, 2017.
XiongYongjie, Chen Huatao, Lin Pengfei, Wang Aihua, Wang Lei, Jin Yaping, ATF6 knockdown decreases apoptosis, arrests the S phase of the cell cycle, and increases steroid hormone production in mouse granulosa cells [J].American Journal of Physiology-Cell Physiology, 312(3): C341-C353, 2017.
ChenHuatao, Gao Lei, Xiong Yongjie, Yang Dan, Li Cuimei, Wang Aihua, Jin Yaping, Circadian clock and steroidogenic-related gene expression profiles in mouse Leydig cells following dexamethasone stimulation [J]. Biochemical and Biophysical Research Communications, 483(1): 294-300, 2017.
ZhuHongmei, Hu Linyong, Liu Jun,Chen Huatao, Cui Chenchen, Song Yujie, Jin Yaping, Zhang Yong, Generation of β-Lactoglobulin-Modified Transgenic goats by Homologous recombination [J]. FEBS Journal, 283(24): 4600-4613, 2016.
Zhao lijia, Isayama Keishiro, Chen Huatao, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki, The nuclear receptor REV-ERBα represses the transcription of growth/differentiation factor 10 and 15 genes in rat endometrium stromal cells [J]. Physiological reports, 4(2): e12663, 2016.
Chen Huatao, Isayama Keishiro, Kumazawa Makoto, Zhao Lijia, Nobuhiko Yamauchi, Yasufumi Shigeyoshi, Seiichi Hashimoto, Masa-aki Hattori, Integration of the nuclear receptor REV-ERBα linked to circadian oscillators in the expression ofAlas1, Ppargc1a, andIl6genes in rat granulosa cells[J]. Chronobiology International, 32(6):739-749, 2015.
Tasaki Hirotaka, Zhao Lijia, Isayama Keishiro, Chen Huatao, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki, Inhibitory role of REB-ERBα in the expression of bone morphogenetic protein gene family in rat uterus endometrium stromal cells [J]. American Journal of Physiology-Cell Physiology, 308(7): C528-C538, 2015.
Isayama Keishiro, Zhao Lijia, Chen Huatao,Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki, Removal of REV-ERBα inhibition contributes to prostaglandin G/H synthase 2 expression in rat endometrial stromal cells [J]. American Journal of Physiology-Endocrinology and Metabolism, 308(8): E650-E661,2015.
Isayama Keishiro, Chen Huatao, Yamauchi Nobuhiko, Hattori Masa-aki, REV-ERBα Inhibits the PTGS2 Expression in Bovine Uterus Endometrium Stromal and Epithelial Cells Exposed to Ovarian Steroids [J]. Journal of reproduction and development, 60(5): 362-370, 2014.
Chen Huatao, Zhao Lijia, Chu Guiyan, Kito Gakushi, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki, FSH induces the development of circadian clockwork in rat granulosa cells via a gap junction protein Cx43-dependent pathway [J]. American Journal of Physiology-Endocrinology and Metabolism,304(6): E566-E575, 2013.
Chen Huatao, Zhao Lijia, Kumazawa Makoto, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki, Down-regulation of core clock gene Bmal1attenuates expression of progesterone and prostaglandin biosynthesis-related genes in rat luteinizing granulosa cells [J]. American Journal of Physiology-Cell Physiology, 304(12): C1131-C1140, 2013.
Tasaki Hirotaka, Zhao Lijia, Isayama Keishiro,Chen Huatao, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hattori Masa-aki, Profiling of circadian genes expressed in the uterus endometrial stromal cells of pregnant rats as revealed by DNA microarray coupled with RNA interference [J]. Frontiers in Endocrinology4: 82, 2013.
Chen Huatao, Chu Guiyan, Zhao Lijia, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki, Rev-erbα regulates circadian rhythms and StARexpression in rat granulosa cells as identified by the agonist GSK4112 [J]. Biochemical and Biophysical Research Communications, 420(2): 374-379, 2012.
Chu Guiyan, Misawa Izumi, Chen Huatao, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki, Contribution of FSH and triiodothyronine to the development of circadian clocks during granulosa cell maturation [J]. American Journal of Physiology-Endocrinology and Metabolism, 302 (6): E645-E653, 2012.
