陳兵(昆蟲遺傳學家)

陳兵(昆蟲遺傳學家)

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陳兵,中國科學院博士,芝加哥大學博士後,瑞士蘇黎世大學訪問學者,河北大學教授,博士生導師,昆蟲學家,進化遺傳學家。主要研究領域為動物逆境適應的生態和進化功能基因組學,涉及昆蟲的耐熱耐寒性、高原低氧適應、熱休克蛋白、表觀遺傳等。共發表論文/論著50餘篇,其中SCI論文30餘篇,第一作者或通訊作者文章近30篇,重要代表性研究成果發表在Nature Communications, Molecular Biology and Evolution, Molecular Ecology, PLoS Genetics, Annual Review of Entomology等期刊上,相關成果被國內國際同行廣泛引用,並被邀請在十多個國際學術會議上報告和給眾多國際雜誌審稿。作為項目和課題負責人主持國家級項目10餘項,包括國家自然科學基金國際地區間合作項目、重大研究計畫項目和面上項目,還開展多項國際和國內合作研究。

基本介紹

  • 中文名:陳兵
  • 外文名:Bing Chen
  • 國籍:中國
  • 民族:漢族
  • 職業:科學研究
  • 畢業院校:中國科學院動物研究所
  • 主要成就:動物逆境生物學
    生態與進化功能基因組學
  • 代表作品:Nature Communications, Molecular Biology and Evolution, Molecular Ecology等
研究方向,教育經歷,工作經歷,主持國家級科研項目(部分),代表論著,學術任職,本科生和研究生教學,國際性學術會議報告或特邀報告,

研究方向

聚焦“動物逆境生物學”(Animal Stress Biology),在動物對環境脅迫適應的分子和遺傳機制方向開展創新型研究。
主要是用生態與進化的功能基因組學的方法和理論,開展動物逆境生物學相關科學問題的研究和相關學科的教學。該方向是動物學(昆蟲學)、生理學、遺傳學和基因組學等學科的前沿交叉領域。
正在開展的研究涉及氧氣(高原缺氧)、水份(乾旱缺水)和種群密度(擁擠)等環境因子,以及熱激蛋白、表觀遺傳(修飾)和適應性變異等分子機制。

教育經歷

2000 – 2003年,博士研究生,中國科學院動物研究所
1997 – 2000年,碩士研究生,華中農業大學植物保護系
1993 – 1997年,本科,長江大學農學院

工作經歷

2018年11月至今,教授,博士生導師,河北大學生命科學學院
2006 – 2018年,副研究員,中國科學院動物研究所,農業蟲害鼠害綜合治理研究國家重點實驗室
2008 – 2010年,訪問學者,瑞士蘇黎世大學(University of Zürich),Department of Biochemistry/Swiss Institute of Bioinformatics(Bing Chen)
2005 – 2006年,博士後,美國芝加哥大學(University of Chicago),Department of Organismal Biology and Anatomy (Bing Chen)
2003 – 2006年,助理研究員,中國科學院動物研究所,農業蟲害鼠害綜合治理研究國家重點實驗室

主持國家級科研項目(部分)

1. 國家自然科學基金委國際(中國-以色列)合作和交流項目(No:31661143048),“高原低氧環境下昆蟲呼吸系統的適應性進化及其遺傳機制研究”,2017-2019年,167萬
2. 國家自然科學基金委面上項目(No:31472048),“飛蝗型變可塑性的父性遺傳及其表觀遺傳機制研究”,2015-2018年,84萬
3. 國家自然科學基金委重大研究計畫培育項目(No:91331106),“飛蝗對青藏高原低氧極端環境遺傳適應的多基因互作機”,2014-2016年,100萬
4. 國家自然科學基金委面上項目(No:31172148),“分子伴侶蛋白Hsp90 對飛蝗滯育特徵進化的調控”,2012-2015年,62萬
5. 國家自然科學基金委面上項目(No:30970343),“斑潛蠅生態適應與熱激蛋白基因表達的進化”,2010-2012年,29萬
6. 國家自然科學基金委面上項目(No:30470291),“溫室對斑潛蠅溫度脅迫耐受性地理分化的調節及其生態學機制”,2005-2007年,20萬
7. 科技部“973”項目子課題(No:2012CB114103),“飛蝗對溫度等環境因子變化的適應機制”,2012 - 2016年,250萬
8. 科技部“973”項目子課題(No:2006CB102002),“斑潛蠅對環境脅迫的適應機制”,2006 - 2011年,126萬

代表論著

  1. Ding Ding, Guangjian Liu, Li Hou, Wanying Gui, Bing Chen*, Le Kang*. 2018. Genetic variation in PTPN1 contributes to metabolic adaptation to high-altitude hypoxia in Tibetan migratory locusts. Nature Communications, 9(1): 49912.(*通信作者,#共同貢獻第一作者)
  2. Bing Chen*, Martin E. Feder, Le Kang*. 2018. Evolution of heat‐shock protein expression underlying adaptive responses to environmental stress. Molecular Ecology, 27(15): 3040-30543.
  3. Bing Chen*, Bo Zhang, Lingling Xu, Qing Li, Feng Jiang, Pengchen Yang, Yanan Xu, and Le Kang. 2017. Transposable element-mediated balancing selection at Hsp90 underlies embryo developmental variation. Molecular Biology and Evolution, 34, 1127-1139
  4. Bing Chen, Ronghui Ma, and Le Kang. 2017. Aerobic respiration by hemocyanin in the embryo of the migratory locust. Insect Molecular Biology, DOI: 10.1111/imb.12310
  5. Phyllis Weintraub, Sonja Scheffer, Diedrich Visser, ...Bing Chen(17), Helga Blanco Metzler. 2017. The Invasive Liriomyza huidobrensis (Diptera: Agromyzidae): understanding its pest status and management globally. Journal of Insect Science, 17, 28-28
  6. Ruben Martin-Blazquez, Bing Chen, Le Kang, Mohammed Bakkali. 2017. Evolution, expression and association of the chemosensory protein genes with the outbreak phase of the two main pest locusts. Scientific Reports, 7(1): 6653.
  7. Bing Chen, Yi Zhang, Xia Zhang, Shili Jia, Shuang Chen, Le Kang. 2016. Genome-wide identification and developmental expression profiling of long noncoding RNAs during Drosophila metamorphosis. Scientific Reports 6, 23330
  8. Bing Chen, Shaoqin Li, Qiang Ren, Xiwen Tong, Xia Zhang, Le Kang. 2015. Paternal epigenetic effects of population density on locust phase-related characteristics associated with heat-shock protein expression. Molecular Ecology, 24:851-62
  9. Bing Chen, Ronghui Ma, Guolan Ma, Xiaojiao Guo, Xiwen Tong, Guowen Tang, Le Kang. 2015. Haemocyanin is essential for embryonic development and survival in the migratory locust. Insect Molecular Biology, 24(5): 517-527
  10. Xiwen Tong, Bing Chen, Li-Hua Huang, Qi-Li Feng, Le Kang. 2015. Proteomic analysis reveals that COP9 signalosome complex subunit 7A (CSN7A) is essential for the phase transition of migratory locust. Scientific Reports, 5:1254211.
  11. Juntao Hu, Bing Chen*, Zhihong Li*. 2014. Thermal plasticity is related to the hardening response of heat shock protein expression in two Bactrocera fruit flies. Journal of Insect Physiology, 67:105-11312.
  12. Xianhui Wang, Xiaodong Fang, Pengcheng Yang, ...Bing Chen(19), et al. 2014. The locust genome provides insight into swarm formation and long-distance flight. Nature Communications, 5:295713.
  13. Zhengyu Zhang, Bing Chen, Dejian Zhao, Le Kang. 2013. Functional modulation of mitochondrial cytochrome c oxidase underlies adaptation to high-altitude hypoxia in Tibetan migratory locust. Proceedings of the Royal Society B: Biological Sciences, 280:20122758
  14. Yuan Luo, Xianhui Wang, Wang, X., Dan Yu, Bing Chen, Le Kang. 2013. Differential responses of migratory locusts to systemic RNA interference via double-stranded RNA injection and feeding. Insect Molecular Biology, 22:574
  15. Bing Chen, Andreas Wagner. 2012. Hsp90 is important for fecundity, longevity, and buffering of cryptic deleterious variation in wild fly populations. BMC Evolutionary Biology, 12:25
  16. Bing Chen, Tieliu Jia, Ronghui Ma, Bo Zhang, Le Kang. 2011. Evolution of Hsp70 gene expression: A role of changes in AT-richness within promoters. PLoS One 6(5): e20308
  17. Le Kang, Bing Chen, Jianing Wei, and Tong-Xian Liu. 2009. Roles of Thermal Adaptation and Chemical Ecology in Liriomyza Distribution and Control. Annual Review of Entomology, 54: 127-45
  18. Bing Chen, Victoria Shilova, Olga Zatsepina, Michael Evgenev, Martin E. Feder. 2008. Location of P element insertions in the proximal promoter region of Hsp70A is consequential for gene expression and correlated with fecundity in Drosophila melanogaster. Cell Stress & Chaperones, 13(1): 11-17
  19. Li-Hua Huang, Bing Chenand Le Kang. 2007. Impact of mild temperature hardening on thermotolerance, fecundity, and Hsp gene expression in Liriomyza huidobrensis. Journal of Insect Physiology, 53:1199-1205
  20. Bing Chen, Jean-Claude Walser, Teresa Rodgers, Rafal Sobota, Molly Burke, Michael Rose, and Martin Feder. 2007. Abundant, diverse, and consequential P element segregate in promoters of small heat-shock genes in Drosophila populations. Journal of Evolutionary Biology, 20(5): 2056-2066
  21. Walser JC, Bing Chen, and Martin E. Feder. 2006. Heat-shock promoters: Targets for evolution by P transposable elements in Drosophila. PLoS Genetics, 2: e165
  22. Shilova Victoria, David Garbuz, Elena Myasniankina, Bing Chen, Michel Evgen’ev, Martin Feder, and Olga Zatsepina. 2006. Remarkable site specificity of local transposition into the hsp70 promoter of Drosophila melanogaster. Genetics, 173: 809-820
  23. Bing Chen and Le Kang. 2005. Can greenhouses eliminate the development of cold resistance of the leafminers? Oecologia, 144: 187-195
  24. Bing Chen and Le Kang. 2005. Implication of pupal cold tolerance for the northern over-wintering range limit of the leafminer Liriomyza sativae (Dipera: Agromyzidae) in China. Applied Entomology and Zoology, 40(3): 437-446
  25. Bing Chen and Le Kang. 2005. Insect population differentiation in response to environmental thermal stress. Science China-Life Sciences, 15(4): 289-296
  26. BingChen and Le Kang. 2004. Variation in cold hardiness of Liriomyza huidobrensis (Dipera: Agromyzidae) along latitudinal gradients. Environmental Entomology, 33(2): 155-164
  27. BingChen and Le Kang. 2002. Cold hardiness and supercooling capacity in the pea leafminer Liriomyza huidobrensis. Cryoletters, 23(3): 173-182
  28. 陳兵. 2019. 環境脅迫適應的生態基因組學. 見:生態基因組學, 康樂主編. 北京: 科學出版社, 付印中
  29. 陳兵, 康樂. 2016. 生態基因組學與分子適應. 見:生態學的現狀與發展趨勢, 于振良主編. 北京: 科學出版社, p42-53
  30. 陳兵,康樂. 2013. 表型可塑性研究. 見:新生物學年鑑2013, 新生物學年鑑編委會主編. 北京:科學出版社, p128-155
  31. 陳兵,康樂. 2005. 昆蟲耐寒性的季節和地理變異. 見:昆蟲學研究-進展與展望, 劉同先, 康樂主編. 北京:科學出版社, p170-203

學術任職

中國昆蟲學會昆蟲生理生化與分子生物學專業委員會委員(2018-)
中國昆蟲學會直翅類昆蟲專業委員會委員(2018-)
《環境昆蟲學報》編委
項目評閱專家:國家自然科學基金委評閱專家;浙江省自然科學基金委同行評議專家;科技部科技評估中心項目評估專家
國際雜誌審稿人,包括Ecology Letters, Molecular Ecology, Insect Molecular Biology, Development Genes and Evolution, Journal of Insect Physiology, Insect Science, Archives of Insect Biochemistry & Physiology, Entomological Research, European Journal of Entomology, Florida Entomology, Gene, Journal of Insect Behavior, Journal of Integrative AgricultureScientific Reports, PLoS ONE,及國內期刊審稿人
中國農業科學院植物保護研究所青年科技人才成長計畫導師

本科生和研究生教學

河北大學本科生基礎課程:遺傳學
中國科學院大學研究生課程:進化生態學(生態基因組學專題)
中國農業大學博士研究生專題課程:逆境生態基因組學
中國林業大學研究生專題課程:生態基因組學
中國農業科學院研究生院專題課程:生態基因組學
中科院動物研究所/安徽大學聯合招生課程:環境基因組學專題

國際性學術會議報告或特邀報告

1) 2018.07 The annual meeting of the Society for Molecular Biology and Evolution in 2018 (SMBE 2018), Yokohama, Japan
Report:Whole Genome Sequencing Reveals Metabolic Adaptation to High-Altitude Hypoxia in a Tibetan Locust
2) 2017.07 The 3rd International Conference of Insect Genomics & the 6th International Symposium on Insect Physiology, Biochemistry and Molecular Biology, Hangzhou, China
Report: Transposable Element-Mediated Natural Mutagenesis of Heat-Shock Proteins underlying Environmental Stress Adaptation
3) 2016.11 The XXV International Congress of Entomology, Orlando, USA
Report: Transgenerational Inheritance of Population Crowding and the Underlying Epigenetic Mechanisms in the Migratory Locust
4) 2015.06 The 5th International Symposium on Insect Physiology, Biochemistry and Molecular Biology, Guangzhou, China
Report: Epigenetic Inheritance of Population Density Effects Associated with Heat-shock Protein Expression in the Migratory Locusts
5) 2013.11 Seminar at the College of Agriculture and Natural Sciences, Lincoln University, Jefferson City, USA
Report: Thermal Stress Adaptation in Two Leafminer Species
6) 2013.06 The 4th International Symposium on Insect Physiology, Biochemistry and Molecular Biology, Nanjing, China
Report: Transgenerational Inheritance of Density-Dependent Phase Change Plasticity in the migratory locust
7) 2013.08 The Eleventh International Conference of Orthopterology, Kunming, China
Report:Transgenerational Epigenetic Inheritance of Population Density-dependent Phase Change Plasticity in the Migratory Locust
8) 2012.08 The XXIV International Conference of Entomology, Daegu, Korea
Report:Identification and Characterization of Long Non-coding RNAs in Two Phases of the Migratory Locust
9) 2011.7 The 3 International Symposium on Insect Physiology, Biochemistry and Molecular Biology, Shanghai, China
Report:Balancing selection for heterozygote advantage associated with a highly repetitive transposon- mediated Hsp90 mutation in Locusta migratoria
10) 2010.04 Swiss Drosophila meeting 2010, Fribourg, Switzerland
Report:The Hsp90 capacitor androbustness to developmental stress in Drosophila melanogaster
11) 2007.6 The 1st International Symposium on Insect Physiology, Biochemistry and Molecular Biology, Jinan, China
Report: Thermal stress adaptation and distribution in the two leafminers
12) 2006.10 Midwest Stress Response and Molecular Chaperone Meeting, Chicago, USA
Report: P elements: A common mechanism of evolution of Hsp genes in Drosophila melanogaster

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