基本介紹
- 中文名：許科帝
- 畢業院校：美國威斯康辛大學
- 學位/學歷：博士
- 專業方向：腦機接口、神經調控、神經修復、動物機器人
- 職務：中國生物醫學工程學會康復工程分會委員
人物經歷,學術成果,發表論文,
人物經歷
2010年7月畢業於浙江大學生物醫學工程與儀器科學學院，獲博士學位，師從鄭筱祥教授從事心血管和神經系統定量生理的研究。2010年9月至2012年9月在美國威斯康辛大學麥迪遜分校藥學院做博士後研究員，主要從事人工皮膚替代生物材料的開發及其生物相容性的研究，期間在Biomaterials、Acta Biomaterilia上發表多篇高水平論文。2012年9月加入浙江大學求是高等研究院從事肯只協腦機接口技術研究。
學術成果
主要研究課題有電刺激、光刺激對大腦皮層結構功煉促譽能的影響，基於光電刺激的感覺信息反饋技術，神經晶片和神經可塑性研究等。針對運動功能控制和恢復的神經工程技術研發擔臭雄，參與了包括 973項目、863計畫在內的多項重大科研項目。相抹擊棵關研究內容獲得了包括國家自然棗道習元科學基金青年科學基金項目、浙江省自然科學基金、國防軍工項目、浙江省科技廳公益項目和教育部博士點基金等多項基金的資助。同時參煮芝與了國家自然基金重點項目和國家國際科技合作專項等項目。學習和工作期間累計發表SCI和EI收入論文27篇，其整芝碑犁中第一作者或通訊作者論文14篇，申請專利1項。
發表論文
Yunqi Zhu, Kedi Xu, Caiyun Xu, Jiacheng Zhang, Jianfeng Ji, Xiaoxiang Zheng, Hong Zhang and Mei Tian*, PET Mapping for Brain-Computer-Interface-Based Stimulation in a Rat Model with Intracranial Electrode Implantation in the Ventro-posterior Medial Thalamus, The Journal of Nuclear Medicine, First published February 25, 2016, doi: 10.2967/jnumed.115.171868； Kedi Xu∗, Jiacheng Zhang, Hong Zhou, Ji Chao Tristan Lee,Xiaoxiang Zheng, A novel turning behavior control method for rat-robot through the stimulation of ventral posteromedial thalamic nucleus, Behavioural Brain Research, (2016), vol.298:150–157； Yipeng Yu, Gang Pan*, Yongyue Gong, Kedi Xu, Nenggan Zheng, Weidong Hua, Xiaoxiang Zheng, Zhaohui Wu, Intelligence-Augmented Rat Cyborgs in Maze Solving, PLOS ONE, February 9, 2016, DOI:10.1371/journal.pone.0147754 Hairui Suo, Kedi Xu*, Hengyi Zhang and Xiaoxiang Zheng, Determination of glucosamine and its derivatives released from photocrosslinked gelatin hydrogels using HPLC, Biomedical Chromatography, February 2016, Volume 30, Issue 2, pages 169–174, Sicong Chen, Hong Zhou, Songchao Guo, Jiacheng Zhang, Yi Qu, Zhouyan Feng, Kedi Xu*, Xiaoxiang Zheng, Optogenetics Based Rat–Robot Control: Optical Stimulation Encodes 'Stop' and 'Escape' Commands, Annals of Biomedical Engineering, August 2015, Vol.43, No.8, pp:1851–1864 Hairui Suo, Kedi Xu* and Xiaoxiang Zheng, Using glucosamine to improve the properties of photocrosslinked gelatin scaffolds, Journal of Biomaterials Applications, 2015, Vol. 29(7) 977–987 Songchao Guo, Sicong Chen, Qiaosheng Zhang, Yueming Wang, Kedi Xu*, and Xiaoxiang Zheng, Optogenetic Activation of the Excitatory Neurons Expressing CaMKII𝛼 in the Ventral Tegmental Area Upregulates the Locomotor Activity of Free Behaving Rats, BioMed Research International, Volume 2014, Article ID 687469, 11 pages Kedi Xu, David Antonio Cantua, Yao Fu, Jaehyup Kim, Xiaoxiang Zheng, Peiman Hematti, W. John Kao*, Thiol-ene Michael-type formation of gelatin/poly(ethylene glycol) biomatrices for three-dimensional mesenchymal stromal/stem cell administration to cutaneous wounds; Acta Biomaterialia; 2013;vol9; 8802–8814; |
Kedi Xu, Yao Fu, WeiJu Chung, Xiaoxiang Zheng, Yujia Cui, Ian C. Hsu, Weiyuan John Kao*, Thiol-ene based biologic/synthetic hybrid biomatrix for 3-D living cell culture. Acta Biomaterialia;2012;vol8; 2504–2516; |
Yao Fu, Kedi Xu, Xiaoxiang Zheng, Alan J. Giacomin, Adam W. Mix, Weiyuan J. Kao*3D cell entrapment in crosslinked thiolated gelatin-poly(ethylene glycol) diacrylate hydrogels; Biomaterials; 2011; vol33; 48-58; |
Kedi Xu, Yi Yang, Ming Yan, Jianan Zhan, Xiao Fu and Xiaoxiang Zheng*, Autophagy plays a protective role in free cholesterol overload-induced death of smooth muscle cells; The Journal of Lipid Research; 2010; vol51; 2581-2590; |
Xu Kedi, Yan Ming, Wang Yongping, Yang Yi, Zheng Xiaoxiang*, Free cholesterol overloading induced smooth muscle cells death and activated both ER- and mitochondrial-dependent death pathway; Atherosclerosis; 2009; vol207; 123-130; |
Ming Yan, Yun Zhang, Kedi Xu, Tao Fu, Haiyan Qin, Xiaoxiang Zheng∗, An in vitro study of vascular endothelial toxicity of CdTe quantum dots; Toxicology; 2011; vol282; 94-103; |
Xiaoyu Liu, Kedi Xu, Ming Yan, Yongping Wang, Xiaoxiang Zheng*, Protective effects of galantamine against Aβ-induced PC12 cell apoptosis by preventing mitochondrial dysfunction and endoplasmic reticulum stress, Neurochemistry International; 2010; Vol 57; 588–599; |
Yi Yang, Kedi Xu, Tatsuro Koike and Xiaoxiang Zheng*, Transport of autophagosomes in neurites of PC12 cells during serum deprivation; Autophagy; 2008; vol 4; 243‑245; |
Tongle Deng,Kedi Xu, Le Zhang, Xiaoxiang Zheng*, Dynamic determination of Ox-LDL-induced oxidative/nitrosative stress in single macrophage by using fluorescent probes; Cell Biology International; 2008; Vol 32; 1425–1432; |
Kedi Xu, Kyle R. Kleinbeck, Weiyuan John Kao*. Multifunctional Biomaterial Matrix for Advanced Wound Healing, Advances in Wound Care; 2012, vol1(2); 75-80; |
Yan Cao, Fang Wang, Qiaosheng Zhang,Kedi Xu, Yiwen Wang* and Xiaoxiang Zheng, Cortical Discrimination of Natural Vibration Stimulation in Rats for a BMI Task, Biomedical Circuits and Systems Conference (BioCAS), 2014 IEEE Conference:22-24 Oct. 2014, Page(s):608 - 611 Yueming Wang, Minlong Lu, Zhaohui Wu, Liwen Tian, Kedi Xu, Xiaoxiang Zheng, Gang Pan, Visual Cue-Guided Rat Cyborg for Automatic Navigation, 2015, IEEE Computational Intelligence Magazine Hong Zhou, Yechao Han, Mingqian Zhao, Xiaoxiang Zheng, Kedi Xu*,Use of non-reward based electrical stimuli of the ventral posteromedial thalamic nucleus to control the turning behavior of rat motor navigation, Multisensor Fusion and Information Integration for Intelligent Systems (MFI), Date of Conference: 28-29 Sept. 2014, Page(s):1-9 Kedi Xu, Yi Qu,Kang Lin,Xiaoxiang Zheng,Yueming Wang*, A BMI-based flashing light recognition system on free-moving rats,April 2014, DOI:10.1109/ICIST.2014.6920559, 2014 4th IEEE International Conference on Information Science and Technology (ICIST) Songchao Guo, Hong Zhou, Yueming Wang, Xiaoxiang Zheng and Kedi Xu*, A Rat-Robot Control System Based on Optogenetics. Applied Mechanics and Materials, 2014, Vol.461 pp:848-852. Songchao Guo, Hong Zhou, Jiacheng Zhang, Kedi Xu* and Xiaoxiang Zheng, A Multi-Electrode Array Coupled with Fiberoptic for Deep-Brain Optical Neuromodulation and Electrical Recording. 35th Annual International Conference of the IEEE EMBS; 2013; 2752-2755; |
Xi Chen, Kedi Xu*, Shuming Ye, Songchao Guo, Xiaoxiang Zheng , A remote constant current stimulator designed for rat-robot navigation; 35th Annual International Conference of the IEEE EMBS; 2013; 2168-2171; |
Sicong Chen, Yi Qu, Songchao Guo, Zhaoyue Shi, Kedi Xu*, Xiaoxiang Zheng*, Encode the “STOP” Command by Photo-Stimulation for Precise Control of Rat-robot; 35th Annual International Conference of the IEEE EMBS; 2013; 2172-2175; |
