解明岐（1987- ），博士研究生，現為西湖大學生命科學學院教師。
基本介紹
- 中文名：解明岐
- 國籍：中國
- 出生日期：1987年
- 畢業院校：瑞士蘇黎世聯邦理工大學
- 職業：大學教師，科研工作者
- 學歷：博士研究生
個人簡介,代表論文,
個人簡介
2017年在瑞士蘇黎世聯邦理工大學（ETH Zürich）獲得博士學位。
2019年8月全職加入了西湖大學生命科學學院，擔任研究員、助理教授（獨立PI）一職，成立生物系統工程實驗室。
代表論文
*: co-first author
1.Bai, P., Liu, Y., Xue, S., Charpin-El Hamri, G., Saxena, P., Ye, H.,Xie, M., and Fussenegger, M. A fully human transgene switch to regulate therapeutic protein production by cooling sensation.Nature Medicine(2019)25, 1266-1273.
2.Xie, M.and Fussenegger, M. Designing cell function: assembly of synthetic gene circuits for cell-biology applications.Nature Reviews Molecular Cell Biology(2018)19, 507-525.
3.Xie, M., Ye, H., Wang, H., Charpin-El Hamri, G., Lormeau, C., Saxena, P., Stelling, J. and Fussenegger, M. β-cell-mimetic designer cells provide closed-loop glycemic control.Science(2016)354, 1296-1301.
4.Xie, M., Ye, H., Charpin El-Hamri, G. and Fussenegger, M. Antagonistic control of a dual-input mammalian gene switch by food additives.Nucleic acids research(2014)42, e116.
5.Ye, H.*,Xie, M.*, Xue, S., Charpin-El Hamri, G., Yin, J., Zulewski, H. and Fussenegger, M. Self-adjusting synthetic gene circuit for correcting insulin resistance.Nature Biomedical Engineering(2017)1,5.
6.Folcher, M.*,Xie, M.*, Spinnler, A. and Fussenegger, M. Synthetic mammalian trigger-controlled bipartite transcription factors.Nucleic acids research(2013)41, e134.
7.Xie, M., Haellman, V. and Fussenegger, M. Synthetic biology - application-oriented cell engineering.Current Opinion in Biotechnology(2016)40, 139-148.
8.Xie, M., Aubel, D. and Fussenegger, M. Closed-Loop Control Systems – the Quest for Precision Medicines for Diabetes.Current Opinion in Systems Biology(2017)5, 32-40.
9.Xie, M.and Fussenegger, M.Mammalian designer cells: Engineering principles and biomedical applications.Biotechnology Journal(2015)10, 1005-1018.
10.Wang, H.,Xie, M., Charpin-El Hamri, G., Ye, H. and Fussenegger, M. Treatment of chronic pain by designer cells controlled by spearmint aromatherapy.Nature Biomedical Engineering(2018)2, 114–123.
11.Bojar, D., Scheller, L., Charpin-El Hamri, G.,Xie, M.and Fussenegger, M. Caffeine-inducible gene switches controlling experimental diabetes.Nature Communications(2018)9:2318.
12.Shao, J., Xue, S., Yu, G., Yu, Y., Yang, X., Bai, Y., Zhu, S., Yang, L., Yin, J., Wang, Y., Liao, S., Guo, S.,Xie, M., Fussenegger, M. and Ye, H. Smartphone-controlled optogenetically engineered cells enable semi-automatic glucose homeostasis in diabetic mice.Science Translational Medicine(2017)9, eaal2298.
13.Wang, H., Ye, H.,Xie, M., Daoud El-Baba, M. and Fussenegger, M. Cosmetics-triggered percutaneous remote control of transgene expression in mice.Nucleic acids research(2015)43, e91.
14.Xue, S., Yin, J., Shao, J., Yu, Y., Yang, L., Wang, Y.,Xie, M., Fussenegger, M. and Ye, H. A Synthetic-Biology-Inspired Therapeutic Strategy for Targeting and Treating Hepatogenous Diabetes.Molecular Therapy(2017)25, 2.
15.Bai, P., Ye, H.,Xie, M., Saxena, P., Zulewski, H., Charpin-El Hamri, G., Djonov, V. and Fussenegger, M. A synthetic biology-based device prevents liver injury in mice.Journal of Hepatology(2016)65, 84-94.
16.Liu, Y., Bai, P., Woischnig, A., Charpin-El Hamri, G., Ye, H., Folcher, M.,Xie, M., Khanna, N. and Fussenegger, M. Immunomimetic designer cells protect mice from methicillin-resistant Staphylococcus aureus infection.Cell(2018)174, 1-12.
