蔣光彬

蔣光彬

蔣光彬，男，漢族，理學博士。碩士研究生導師，在桂林理工大學化學與生物工程學院從事教學與科研工作。

基本介紹

人物經歷,研究方向,主要成果,代表論文,

人物經歷

1. 2018.07—至今 桂林理工大學，化學與生物工程學院，化學與化工教研室任教，2018年晉升講師，2021年晉升副教授。
2. 2020.07—2020.12月 桂林三棱生物科技有限公司，專項調研與方案策劃；
3. 2015.09—2018.06 華南理工大學，化學與化工學院，有機化學專業，博士；

研究方向

（1）綠色有機合成方法學研究：專注於探索電化學與光催化在有機合成中的套用，旨在實現複雜功能分子的高效製備與結構修飾，為先導化合物的發現提供新技術和新方法；
（2）新型抗菌、抗腫瘤藥物分子的合成及生物活性機制研究：聚焦於新型金屬配合物（如釕、銥等）及氮雜環化合物的設計與合成，研究其在抗腫瘤及抗菌領域的套用價值，明確活性機制及構效關係。

主要成果

主持的科研項目包括：國家自然科學基金項目2項，廣西自然科學基金項目2項，廣西科技基地和人才專項1項，廣西電磁化學功能物質重點實驗室-主任基金1項，桂林理工大學科研啟動經費1項。
在Green. Chem.; Org. Lett.; Chem. Commun.; Org. Chem. Front.; Adv.Synth. Catal.; J. Org. Chem.; Appl. Organomet. Chem.; Org. Biomol. Chem.;J. Inorg. Biochem.; Spectrochim. Acta. A Mol. Biomol. Spectrosc.;New. J. Chem.; Mol. Catal.; Dalton Trans.等國內外學術期刊上發表SCI收錄論文40餘篇。

代表論文

1. Jiawei Xu, Wenxiu Huang, Mingzhe Li, Chen Kang, Guangbin Jiang*,Fanghua Ji*, Selective Synthesis ofAmides and α-Ketoamides via Electrochemical Decarboxylation and Dehydration, J. Org. Chem., 2024, 89, 10498–10510.
2. Shuai Zhang, Zhihua Zhang, Changsheng Qin, Meiqian Hu, Jingfang Wang,Fanghua Ji*, Guangbin Jiang*,Electrochemical Oxidative Functionalization of Pyrazolin-5-ones: Access to4-Quinoxalinone-Substituted Pyrazoles, Adv. Synth. Catal., 2024,https://doi.org/10.1002/adsc.202400825.
3. Changsheng Qin, Jiangfang Wang, Fang Gao, ShuaiZhang, Meiqian Hu, Zhihua Zhang, Fanghua Ji*, Guangbin Jiang*, DirectN-H Heteroarylation of NH-Sulfoximines under Electrochemical Conditions, Mol. Catal., 2024, 568, 114485.
4. Zhicheng Xiong, Hongsheng Nie, Shuai Zhang, Meiqian Hu, Changsheng Qin,Shoucai Wang, Fanghua Ji*, Guangbin Jiang*, Electrochemically Driven Selective Removal of the S=N Bond DirectingGroup Using Cyclohexanone Oxime as the Mediator, J. Org. Chem., 2023, 88, 4334−4344.
5. Hongsheng Nie, Zhicheng Xiong, Meiqian Hu, Shuai Zhang, Changsheng Qin,Shoucai Wang, Fanghua Ji*, Guangbin Jiang*, Copper-Catalyzed Sulfonylation Reaction of NH-Sulfoximines withAryldiazonium Tetrafluoroborates and Sulfur Dioxide: Formation of N-SulfonylSulfoximines; J. Org. Chem., 2023,88, 2322–2333.
6. ChenKang, Mingzhe Li, Wenxiu Huang, Shoucai Wang, Mengyu Peng, Longqiang Zhao, GuangbinJiang,* Fanghua Ji,* Electrochemical N-acylation and N-α-ketoacylation ofsulfoximines via the selective decarboxylation and dehydration of α-ketoacids. Green Chem., 2023, 25, 8838–8844.
7. MingzheLi, Mengyu Peng, Wenxiu Huang, Longqiang Zhao, Shoucai Wang, Chen Kang, GuangbinJiang,* Fanghua Ji,* Electrochemical Oxidative Carbonylation of NH‑Sulfoximines. Org. Lett., 2023, 25, 7529−7534.
8. MengyuPeng, Mingzhe Li, Longqiang Zhao, Wenxiu Huang, Shoucai Wang, Kang Chen, GuangbinJiang,* Fanghua Ji.* Electrochemical oxidative carbonylation of hydrazides forthe synthesis of 1,3,4-oxadiazole-2(3H)-ones. Org. Chem. Front., 2023, 10,5680–5684.
9. Guang Yang, Zhicheng Xiong, Hongsheng Nie, Meiqin He, Qiong Feng, XuanLi, Huabin Huang, Shoucai Wang, Fanghua Ji*, Guangbin Jiang*, Copper-Catalyzed Divergent C-H FunctionalizationReaction of Quinoxalin-2(1H)-ones andAlkynes Controlled by N1-substituentsfor the Synthesis of (Z)-enaminonesand Furo[2,3-b]quinoxalines; Org. Lett., 2022, 24, 1859−1864.
10. Guang-Bin Jiang,* Wen-Yao Zhang, Miao He, Yi-Ying Gu, Bai Lan, Yang-Jie Wang, Qiao-Yan Yi,Fan Du. Systematic evaluation of the antitumor activity of three rutheniumpolypyridyl complexes; J. Inorg. Biochem.,2021, 225, 111616.
11. Showcai Wang, Siyu Zhang, Meichen Liu, Jiawang Zang, Guangbin Jiang* and Fanghua Ji.* Palladium-catalyzed C3-selective C–H oxidativecarbonylation of imidazo[1,2-a]pyridines with CO and alcohols: a way to accessesters; Org. Chem. Front. 2020, 7,697-701.
12. Guang-Bin Jiang,* Wen-Yao Zhang, Miao He, Yi-Ying Gu, Lan Bai,Yang-Jie, Wang, Qiao-Yan Yi, Fan Du. New ruthenium polypyridyl complexesfunctionalized with fluorine atom or furan: Synthesis, DNA-binding,cytotoxicity and antitumor mechanism studies; Spectrochim. Acta. A Mol. Biomol. Spectrosc., 2020, 227, 117534.
13. Guangbin Jiang, Weigao Hu, Jianxiao Li, Chuanle Zhu, Wanqing Wu,Huanfeng Jiang.* Palladium-catalyzed primaryamine-directed regioselective mono- and di-alkynylation of biaryl-2-amines. Chem. Commun., 2018, 54, 1746-1749.14.
14. Guangbin Jiang, Jianxiao Li, Chuanle Zhu, Wanqing Wu, Huanfeng Jiang.* Palladium-Catalyzed Sequential Nucleophilic Addition/Oxidative Annulation of Bromoalkynes with Benzoic Acids To Construct Functionalized Isocoumarins. Org. Lett., 2017, 19, 44440-4443.
15. Guangbin Jiang, Yangyin Xie, Ganjian Lin, Hongliang Huang, Zhenghua Liang, Yunjun Liu.* Synthesis, characterization, DNA interaction, antioxidant and anticancer activity studies of ruthenium(II) polypyridyl complexes. J Photoch. Photobio. B., 2013, 129, 48-56.

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