蔡倩， 男，研究員，博士，致力於藥物合成工藝和有機化學的研究。
基本介紹
- 中文名：蔡倩
- 性別：男
- 職稱：研究員
- 工作單位：中國科學院廣州生物醫藥與健康研究院
基本信息,簡歷,研究領域,獲獎及榮譽,代表論著,
基本信息
職 務:
學 歷: 博士
通訊地址: 廣州蘿崗區科學城開源大道190號
簡歷
1997-2001, 南開大學化學系 學士
2001-2006 中國科學院上海有機化學研究所 博士
2006-2009 美國密西根大學博士後
2009- 中國科學院廣州生物醫藥與健康研究院
研究領域
1、藥物合成工藝和有機化學研究
2、基於結構基礎合理設計合成小分子化合物做為抗腫瘤以及其它疾病藥物，例如蛋白質激酶小分子抑制劑，聚糖蛋白質小分子抑制劑等。
獲獎及榮譽
2005 上海市科技進步一等獎 (第五獲獎人)
2007 國家自然科學二等獎 （第五獲獎人）
2008-2009 中國科學院廣東省分院、廣州市科學院“優秀青年科技工作者”
代表論著
1. Cai, Qian; Sun, Haiying; Peng, Yuefeng, Lu, Jianfeng; Nikolovaks-Coleska, Zaneta; McEachern, Donna; Liu, Liu; Qiu, Su; Yang, Chao-Yie; Miller, Rebecca; Yi, Han; Zhang, Tao; Sun, Duxin; Kang, Sanmao; Guo, Ming; Leopold, Lance; Yang, Dajun; Wang, Shaomeng. A Potent and Orally Active Angagonist (SM-406/AT-406) of Multiple Inhibitor of Apoptosis Proteins (IAPs) in Clinical Development for Cancer Treatment. J. Med. Chem
2. Cai，Qian；Zhou, Fengtao; Xu, Tianfeng; Fu, Liangbing; Ding, Ke. Copper-Catalyzed Tandem Reactions of 1-(2-Iodoary) -2-yn-1-ones with Isocyanides for the Synthesis of 4-Oxo-indeno[1,2-b]pyrroles. Org. Lett.
3. Cai, Qian; Li, Zhengqiu; Wei, Jiajia; Fu, Liangbin; Ha, Chengyong; Pei, Duanqing ; Ding, Ke. Synthesis of Aza-Fused Polycyclic Quinolines through Copper-Catalyzed Cascade Reactions Org. Lett
4. Cai, Qian; Li, Zhengqiu; Wei, Jiajia; Ha, Chengyong; Pei, Duanqing ; Ding, Ke. Assembly of Indole-2-Carboxylic Acid Esters through a Ligand-Free Copper-Catalysed Cascade Process. Chem. Commun.
5. Wang, Deping; Cai, Qian; Ding, Ke. An Efficient Copper-Catalyzed Amination of Aryl Halides by Aqueous Ammonia. Adv. Synth. Catal
6. Cai, Qian; Zhang, Hui; Zou, Benli; Xie, Xiaoan; Zhu, Wei; He, Gang; Wang, Jing; Pan, Xianhua; Chen, Yu; Yuan, Qiliang; Liu, Feng; Lu, Biao; Ma, Dawei. Amino Acid-Promoted Ullmann-type Coupling Reactions and Their Applications in Organic Synthesis. Pure Appl. Chem
7. Ma, Dawei; Cai, Qian. Copper/Amino Acid Catalyzed Cross-Couplings of Aryl and Vinyl Halides with Nucleophiles. Acc. Chem. Res
8. Sun, Haiying; Nikolovska-Coleska, Zaneta; Yang, Chao-Yie; Qin, Dongguang; Lu, Jianfeng; Qiu, Su; Bai, Longchuan; Peng, Yuefeng; Cai, Qian; Wang, Shaomeng. Design of Small-Molecule Peptidic and Nonpeptidic Smac Mimetics. Acc. Chem. Res.
9. Cai, Qian; Zou, Benli; Ma, Dawei. Mild Ullmann-type biaryl ether formation reaction via Combination of ortho-substituent and ligand effects. Angew. Chem. Int. Ed.
