蔡佩娥

蔡佩娥

蔡佩娥,馬來西亞籍,中山大學孫逸仙紀念醫院醫學研究中心研究員、博士生導師,中山大學百人計畫引進人才,論文潤色小組組長及學術規範辦公室成員。

基本介紹

  • 中文名:蔡佩娥
  • 國籍:馬來西亞
  • 執業地點:中山大學孫逸仙紀念醫院
  • 職務:博士生導師
研究方向,論文發表,

研究方向

研究利用多種生物回響型納米給藥系統靶向調節腫瘤微環境用於腫瘤免疫治療。負責High-level Talent Special Funding Scheme of Sun Yat-Sen Memorial Hospital、國家自然科學基金面上項目、The Research Fund for International Young Scientists、國家自然青年科學基金項目等多個課題項目,獲批“三個三”工程青年拔尖人才、中山大學優秀青年教師培育等項目。圍繞“高分子納米材料”和“腫瘤靶向治療”方向在 Cancer Cell (IF 26.602), Advanced Materials (IF 27.398), ACS Nano (IF 14.588),Nano Letters (IF 11.238), AngewandteChemie International Edition (IF 12.959), Theranostics (IF 8.579), Biomaterials (IF 10.317), Journal of Controlled Release (IF 7.727)等國際 SCI 期刊發表論文51篇(其中第一作者或通訊作者發表論文共26篇)。授權/受理權利 3 項(韓國專利 2 項,國際專利 1 項),專利申請受理項目3項(中國專利3項)。發表 ACS Nano研究論文入選月最高閱讀 10 篇論文之一;發表Theranostics研究論文被 Radiology Newsletter 評為韓國年度最佳 4 篇論文之一;研究成果被 Nature Middle East, Cell Therapy News 以及 Prostate Cell News 等專題報導。

論文發表

Li X, Liang S, Tan CH, Cao S, Xu X, Saw PE#, Tao W. Nanocarriers in the Enhancement of Therapeutic Efficacy of Natural Drugs. BIO Integration. DOI:10.15212/bioi-2020-0040. (影響因子:-)
Saw PE, Xu X, Kang BR, Lee J, Lee YS, Kim C, Kim S, Kang SH, Na JY, Moon HJ, Kim JH, Park YK, Yoon W, Kim JH, Kwon TH, Choi C, Jon S, Chong K. Extra-domain B of fibronectin as an alternative target for drug delivery and a cancer diagnostic and prognostic biomarker for malignant glioma. Theranostics. 2021; 11(2): 941-957. (影響因子: 8.579)
Xu Y, Jiang Q, Liu H, Xiao X, Yang D, Saw PE# and Luo B. DHX37 Impacts Prognosis of Hepatocellular Carcinoma and Lung Adenocarcinoma through Immune Infiltration. Journal of Immunology Research. doi.org/10.1155/2020/8835393 (影響因子:3.327)
Chen Z, Lin C, Song B, Li C, Qiu J, Li S, Lin S, Luo W, Fu Y, Fang G, Li W, Saw PE#, Ding Y. Spermidine activates RIP1 deubiquitination to inhibit TNF-α-induced NF-κB/p65 signaling pathway in osteoarthritis. Cell Death and Disease. 2020 Jul 6;11(7):503. (影響因子: 6.304)
Cao S, Liu X, Li X, Lin C, Zhang W, Tan CH, Liang S, Luo B, Xu X, Saw PE. Shape matters: comprehensive analysis of star-shaped lipid nanoparticles. Frontiers in Pharmacology. 2020 Apr 30;11:539. (影響因子: 4.225)
Saw PE, Xu X, Chen J, Song E. Non-coding RNA: the new central dogma of cancer biology. Science China Life Sciences. 2021 Jan;64(1):22-50. (影響因子: 4.611)
Saw PE, Xu X, Zhang M, Cao S, Farokhzad OC, Wu J. Nanostructure Engineering by Simple Tuning of Lipid Combinations. Angew Chem Int Ed Engl. 2020 Apr 6;59(15):6249-6252. (影響因子: 12.959)
Saw PE, Yao H, Lin C, Tao W, Farokhzad O, Xu X. Stimuli-Responsive Polymer-Prodrug Hybrid Nanoplatform for Multistage siRNA Delivery and Combination Cancer Therapy. Nano Letters. 2019 Sep 11;19(9):5967-5974. (影響因子: 11.238)
Saw PE, Song E. Phage Display Technique for Tumor-targeting High Affinity Peptide Identification. Protein & Cell. 2019 Nov;10(11):787-807 (影響因子: 10.164)
Li S, Saw PE*, Lin C, Nie Y, Tao W, Farokhzad OC, Zhang L, Xu X. Redox-responsive polyprodrug nanoparticles for targeted siRNA delivery and synergistic liver cancer therapy. Biomaterials. 2020 Mar;234:119760. (影響因子: 10.317)

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