王品美，女，博士，浙江大學副教授、碩士生導師。
基本介紹
- 中文名：王品美
- 學位/學歷：博士
- 職業：教師
- 專業方向：海洋微生物資源、微生物生物合成研究
- 職務：碩士生導師
- 職稱：副教授
- 任職院校：浙江大學
- 性別：女
個人經歷,研究方向,教學工作,主講課程,指導實習,學術成果,
個人經歷
2005年本科畢業於浙江大學生命科學學院生物科學系，之後免試推薦在浙江大學生命科學學院微生物系攻讀博士學位，2010年博士畢業後在浙江大學生命科學學院開展博士後研究，2012年7月到浙江大學海洋工程與科學系工作，2013-2014年到美國威斯康星麥迪遜分校醫學微生物與免疫系訪問，2016年在浙江大學海洋學院晉升為副教授和博士生導師。
研究方向
· 海洋微生物資源 · 微生物生物合成研究
主要研究領域為海洋微生物和微生物生物合成學，重點研究模式微生物釀酒酵母、海洋微生物遺傳代謝相關功能基因的作用及分子調控機制，構建酵母、麴黴為底盤生物，挖掘海洋微生物次級代謝生物合成途徑，激活次級代謝生物合成沉默基因簇的表達，獲得新型活性物質，套用於環境治理、醫藥及工農業等領域。
教學工作
主講課程
(1) 本科生專業方向必修課 “海洋微生物學及實驗”
(2) 研究生專業學位課程“高級微生物學”
指導實習
(1) 原2013級-2015級本科生大一學年暑期的“海岸帶、海島實習”
(2) 原2013級-2016級本科生“科研實習”、“生產實習”
學術成果
迄今共發表SCI論文19篇，主持國家自然科學基金、浙江省項目等4項。
1.Li X, Xu JZ, Wang WJ, Chen YW, Zheng DQ, Di YN, Li P,Wang PM*, and Li YD*, Genome Sequencing and Evolutionary Analysis of Marine Gut FungusAspergillussp. Z5 fromLigia oceanica. Evol Bioinform Online, 2016; 12: 1-4. Pubmed Record
2.Wang P-M,Choera T, Wiemann P, Pisithkul T, Amador-Noguez D, and Keller NP*, TrpE feedback mutants reveal roadblocks and conduits towards increasing secondary metabolism inAspergillus fumigatus. Fungal Genetics and Biology, 2016; 89: 102-113. Pubmed Record
3.Wang P, Zhao S, Liu Y, Ding W, Qiu F, and Xu J*, Asperginine,an Unprecedented Alkaloid from the Marine-derived FungusAspergillussp.Natural Product Communications, 2015; 10: 1363-1364. Pubmed Record
4. Li O, Qian CD, Zheng DQ,Wang PM, Liu Y, Jiang XH, and Wu XC*, Two UDP-glucuronic acid decarboxylases involved in the biosynthesis of a bacterial exopolysaccharide inPaenibacillus elgii.Appl Microbiol Biotechnol, 2015; 99: 3127-39. Pubmed Record
5. Zhang K, Tong M, Gao K, Di Y,Wang P, Zhang C, Wu X*, and Zheng D*, Genomic reconstruction to improve bioethanol and ergosterol production of industrial yeastSaccharomyces cerevisiae. J Ind Microbiol Biotechnol, 2015; 42: 207-18. Pubmed Record
6.Wang PM, Zheng DQ, Chi XQ, Li O, Qian CD, Liu TZ, Zhang XY, Du FG, Sun PY, Qu AM, and Wu XC*, Relationship of trehalose accumulation with ethanol fermentation in industrialSaccharomyces cerevisiaeyeast strains. Bioresour Technol, 2014; 152: 371-6. Pubmed Record
7. Li O, Liu A, Lu C, Zheng DQ, Qian CD,Wang PM, Jiang XH, and Wu XC*, Increasing viscosity and yields of bacterial exopolysaccharides by repeatedly exposing strains to ampicillin. Carbohydr Polym, 2014; 110: 203-8. Pubmed Record
8. Liu Y, Zhao S, Ding W,Wang P, Yang X, and Xu J*, Methylthio-aspochalasins from a marine-derived fungusAspergillussp. Mar Drugs, 2014; 12: 5124-31. Pubmed Record
9. Zheng DQ, Chen J, Zhang K, Gao KH, Li O,Wang PM, Zhang XY, Du FG, Sun PY, Qu AM, Wu S, and Wu XC*, Genomic structural variations contribute to trait improvement during whole-genome shuffling of yeast. Appl Microbiol Biotechnol, 2014; 98: 3059-70. Pubmed Record
10. Li O, Lu C, Liu A, Zhu L,Wang PM,Qian CD, Jiang XH, and Wu XC*, Optimization and characterization of polysaccharide-based bioflocculant produced byPaenibacillus elgiiB69 and its application in wastewater treatment. Bioresour Technol, 2013; 134: 87-93. Pubmed Record
11. Zheng DQ, Liu TZ, Chen J, Zhang K, Li O, Zhu L, Zhao YH, Wu XC*, andWang PM*, Comparative functional genomics to reveal the molecular basis of phenotypic diversities and guide the genetic breeding of industrial yeast strains. Appl Microbiol Biotechnol, 2013; 97: 2067-76. Pubmed Record
12. Tao X, Zheng D, Liu T,Wang P, Zhao W, Zhu M, Jiang X, Zhao Y, and Wu X*, A novel strategy to construct yeastSaccharomyces cerevisiaestrains for very high gravity fermentation. PloS one, 2012; 7: e31235. Pubmed Record
13.Wang PM, Zheng DQ, Liu TZ, Tao XL, Feng MG, Min H, Jiang XH, and Wu XC*, The combination of glycerol metabolic engineering and drug resistance marker-aided genome shuffling to improve very-high-gravity fermentation performances of industrialSaccharomyces cerevisiae. Bioresour Technol, 2012; 108: 203-10. Pubmed Record
14. Zheng DQ,Wang PM, Chen J, Zhang K, Liu TZ, Wu XC*, Li YD, and Zhao YH, Genome sequencing and genetic breeding of a bioethanolSaccharomyces cerevisiaestrain YJS329. BMC Genomics, 2012; 13: 479. Pubmed Record
15.Wang PM, Zheng DQ, Ding R, Chi XQ, Tao XL, Min H, and Wu XC*, Improvement of ethanol production inSaccharomyces cerevisiaeby hetero-expression ofGAPNandFPS1deletion. Journal of Chemical Technology and Biotechnology, 2011; 86: 1205-1210. Pubmed Record
16.Wang PM, Wu X-C*, Chi X-Q, Li Y-D, Zheng D-Q, Ding R, and Min H, Development and application of RAPD-SCAR markers to identify intra-species hybrids of industrialSaccharomyces cerevisiae. World Journal of Microbiology and Biotechnology, 2011; 27: 185-188. Pubmed Record
17. Zheng DQ, Wu XC*, Tao XL,Wang PM, Li P, Chi XQ, Li YD, Yan QF, and Zhao YH, Screening and construction ofSaccharomyces cerevisiaestrains with improved multi-tolerance and bioethanol fermentation performance. Bioresour Technol, 2011; 102: 3020-7. Pubmed Record
18. Zheng D-Q, Wu X-C,Wang PM, Chi X-Q, Tao X-L, Li P, Jiang X-H, and Zhao Y-H, Drug resistance marker-aided genome shuffling to improve acetic acid tolerance inSaccharomyces cerevisiae. Journal of industrial microbiology & biotechnology, 2011; 38: 415-422. Pubmed Record
19. Wu X, Chi X,Wang P, Zheng D, Ding R, and Li Y*, The evolutionary rate variation among genes of HOG-signaling pathway in yeast genomes. Biology direct, 2010; 5: 46. Pubmed Record。
