基本介紹
人物經歷,學術論文,
人物經歷
李登文，於1993年進入南開大學微生物系學習。 1997年本科畢業，同年免試繼續攻讀碩士研究生，研究的主要內容是“酵母金屬硫蛋白的研究”，於2000年獲得碩士學位。2002年進入南開大學生物化學與分子生物學系，開始博士研究生階段的學習，研究方向是“組蛋白 H3 磷酸化與細胞有絲分裂的關係研究”，2005年獲得博士學位，並留校工作。參與“生物化學”、“普通生物學”等課程的教學工作；科研工作主要集中在細胞形態結構與功能方面的研究，以第一作者在國際和國核心心刊物發表多篇論文。
學術論文
- Xie Songbo, Yang Yang, Lin Xiaochen, Zhou Jun, Li Dengwen*, Liu Min*, Characterization of a novel EB1 acetylation site important for the regulation of microtubule dynamics and cargo recruitment, Journal of Cellular Physiology, 2018, 233(3): 2581-2589
- Shi Xingjuan*, Li Dengwen, Wang Yujue, Liu Shiyu, Qin, Juan, Wang Jun, Ran Jie, Zhang Yu, Huang Qinghai, Liu Xiangdong, Zhou Jun, Liu Min*, Discovery of centrosomal protein 70 as an important player in the development and progression of breast cancer, American Journal of Pathology, 2017, 187(3): 679-688
- Yang Yang, Mu Tianhao, Li Te, Xie Songbo, Zhou Jun, Liu Min*, Li Dengwen*, Effects of FSTL1 on the proliferation and motility of breast cancer cells and vascular endothelial cells, Thoracic Cancer, 2017, 8(6):606-612
- Zhang Yijun, Luo Youguang, Lyu Rui, Chen Jie, Liu Ruming, Li Dengwen, Liu Min, Zhou Jun*, Proto-Oncogenic Src Phosphorylates EB1 to regulate the microtubule-focal adhesion crosstalk and stimulate cell migration, Theranostics, 2016, 6(12):2129-2140
- Yang Yunfan, Liu Min,Li Dengwen, Ran Jie, Gao Jinmin, SuoShaojun, Sun Shao-Cong, Zhou Jun, CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation，Proceedings of the National Academy of Sciences of the United States of America，2014, 111(6): 2158-2163
- LiDengwen, GaoJinmin, YangYunfan, SunLei, SuoShaojun, LuoYouguang, ShuiWenqing, ZhouJun*, LiuMin*, CYLDcoordinates with EB1 to regulate microtubule dynamics and cell migration, Cell Cycle, 2014, 13(6): 974-983
- LiDengwen, SunXiaodong, ZhangLinlin, YanBing, XieSongbo, LiuRuming, LiuMin, ZhouJun*, Histone deacetylase 6 and cytoplasmic linker protein 170 function together to regulate the motility of pancreatic cancer cells, Protein & Cell, 2014, 5(3): 214-223
- Zhang Linlin, Liu Ningning, Xie Songbo, He Xianfei, Zhou Jun, LiuMin, Li Dengwen*, HDAC6 regulates neuroblastoma cell migration and may play a role in the invasion process, Cancer Biology & Therapy, 2014, 15(11): 1561-1570
- Peng Guoyuan, Ren Yuan, Sun Xiaodong, Zhou Jun, Li Dengwen*, Inhibition of farnesyltransferase reduces angiogenesis by interrupting endothelial cell migration. Biochemical Pharmacology 2012, 83(10):1374-1382
- Li Dengwen, Xie Songbo, Ren Yuan, Huo Lihong, Gao Jinmin, Cui Dandan, Liu Min, Zhou Jun*, Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner. Protein & Cell 2011, 2(2):150-160
