曹家雪

曹家雪，中共黨員，講師，碩士生導師，四川省生物信息學學會會員。

基本介紹

• 中文名：曹家雪
• 國籍：中國

研究方向

1.基因編輯技術

2.羊的重要經濟性狀研究

3.表觀遺傳學

教育經歷

1.2014-09至2016-09,哈佛大學,人類進化生物系,聯合培養博士,導師: Terence D Capellini

2.2011-09至2014-08,中國農業科學院北京畜牧獸醫研究所,畜禽資源與遺傳育種系,聯合培養博士,導師:杜立新

3.2010-09至2016-12,四川農業大學,動物科技學院,博士,導師:張紅平

4.2006-09至2010-06,四川農業大學,動物科技學院,學士

工作經歷

2017-01至現在,四川農業大學,動物科學系,講師

教學課程

《畜牧學通論》

科研項目

國家自然科學基金委員會，青年科學基金項目，31802048,NamiRNA-193b-3p靶向IGF2BP1調控山羊骨骼肌衛星細胞增殖分化的分子機制，2019-01至2021-12，23萬元，在研，主持

社會服務

四川省科學技術廳，2019年度“三區”人才支持計畫，南江黃羊育種規劃、養殖生產技術諮詢。

代表論文

(1) Daniel Richard; Zun Liu;Jiaxue Cao; Ata M Kiapour; Jessica Willen; Siddharth Yarlagadda; Evelyn Jagoda; Vijaya B. Kolachalama; Gary H. Chang; Jakob T. Sieker; Johannes Konrad; Pushpanathan Muthuirulan; Mariel Young; Anand Masson; David E. Maridas; Shayan Hosseinzadeh; Roman Krawetz; Vicki Rosen; Neil Roach; Terence D. Capellini. Evolutionary Selection and Constraint on Human Knee Chondrocyte Regulation Impacts Osteoarthritis Risk, CELL, 2020, Accepted.

(2) Steven K Pregizer ; Ata M Kiapour ; Mariel Young; Hao Chen; Michael Schoor; Zun Liu;Jiaxue Cao; Vicki Rosen; Terence D Capellini. Impact of broad regulatory regions on Gdf5 expression and function in knee development and susceptibility to osteoarthritis, Annals of the Rheumatic Diseases, 2018, 77(3)

(3) Terence D Capellini ; Hao Chen ;Jiaxue Cao; Andrew C Doxey; Ata, M Kiapour; Micheal Schoor; David M Kingsley. Ancient selection for derived alleles at a GDF5 enhancer influencing human growth and osteoarthritis risk, Nature Genetics, 2017, 49(8): 1202~1210

(4)Jiaxue Cao; Caihong Wei ; Shuzhen Zhang; Terence D Capellini; Li Zhang; Fuping Zhao; Li Li; Tao Zhong; Linjie Wang; Lixin Du ; Hongping Zhang. Screening of reproduction-related single-nucleotide variations from MeDIP-seq data in sheep, Molecular Reproduction and Development, 2016, 83(11): 958~967

(5) Caihong Wei ; Huihua Wang ; Gang Liu; Fuping Zhao; James W Kijas, Youji Ma; Jian Lu; Li Zhang;Jiaxue Cao; Mingming Wu; Guangkai Wang; Ruizao Liu; Zhen Liu; Shuzhen Zhang; Chousheng Liu ; Lixin Du. Genome-wide analysis reveals adaptation to high altitudes in Tibetan sheep, Scientific Reports, 2016, 6: e26770

（5）Mingming Wu ; Caihong Wei ; Zhengxing Lian; Ruizao Liu; Caiye Zhu, Huihua Wang;Jiaxue Cao; Yuelei Shen; Fuping Zhao; Li Zhang; Zhu Mu; Yayu Wang; Xiaogang Wang ; Lixin Du ; Chuduan Wang. Rosa26-targeted sheep gene knock-in via CRISPR-Cas9 system, Scientific Reports, 2016, 6: e24360

(7)Jiaxue Cao; Caihong Wei ; Dongming Liu; Huihua Wang; Mingming Wu; Zhiyuan Xie; Terence D Capellini; Li Zhang; Fuping Zhao; Li Li; Tao Zhong; Linjie Wang; Jian Lu; Ruizao Liu; Shifang Zhang; Yongfei Du; Hongping Zhang; Lixin Du. DNA methylation Landscape of body size variation in sheep Scientific Reports, 2015, 5: e13950

(8)曹家雪;張紅平;杜立新.環境因素對DNA甲基化的影響遺傳2013 35(7): 839~846

(9) Jian Lu ; Caihong Wei ; Xiaoning Zhang; Lingyang Xu; Shifang Zhang; Jiashen Liu;Jiaxue Cao; Fuping Zhao; Li Zhang; Bichun Li ; Lixin Du. The effect of myostatin silencing by lentiviral-mediated RNA interference on goat fetal fibroblasts, Molecular Biology Reports , 2013, 40(6): 4101~4108

(10)曹家雪;董恩妮;李利;李秋;張紅平;王永;鄧中寶;龔華斌.山羊胰島素樣生長因子結合蛋白1基因的生物信息學分析,中國畜牧獸醫, 2012, 39(5): 56~62