房鵬飛,男,中國科學院大學專任教師。
基本介紹
- 中文名:房鵬飛
- 國籍:中國
- 畢業院校:中國科學技術大學
- 學位/學歷:博士
人物經歷,教育背景,工作經歷,研究方向,科研成果,
人物經歷
教育背景
2005-09--2010-06 中國科學技術大學 博士
2001-09--2005-07 中國科學技術大學 學士
工作經歷
2016-01~現在, 中國科學院上海有機化學研究所, 研究員
2010-08~2016-01,美國Scipps研究所, 博士後助理研究員
研究方向
化學生物學
科研成果
發表論文
[1] Wang, Yong, Zhou, JingBo, Zeng, QiYu, Wu, Siqi, Xue, MeiQin, Fang, Pengfei, Wang, EnDuo, Zhou, XiaoLong. Hearing impairment-associated KARS mutations lead to defects in aminoacylation of both cytoplasmic and mitochondrial tRNA(Lys). SCIENCE CHINA-LIFE SCIENCES[J]. 2020, 63(8): 1227-1239, http://lib.cqvip.com/Qikan/Article/Detail?id=7102433157.
[2] Zhou, XiaoLong, Chen, Yun, Zeng, QiYu, Ruan, ZhiRong, Fang, Pengfei, Wang, EnDuo. Newly acquired N-terminal extension targets threonyl-tRNA synthetase-like protein into the multiple tRNA synthetase complex. NUCLEIC ACIDS RESEARCH[J]. 2019, 47(16): 8662-8674, [3] Kong, Jiwon, Fang, Pengfei, Madoux, Franck, Spicer, Timothy P, Scampavia, Louis, Kim, Sunghoon, Guo, Min. High-Throughput Screening for Protein Synthesis Inhibitors Targeting Aminoacyl-tRNA Synthetases. SLAS DISCOVERY[J]. 2018, 23(2): 174-182, https://www.webofscience.com/wos/woscc/full-record/WOS:000423048900007.
[4] Fang, Pengfei, Guo, Min. Structural characterization of human aminoacyl-tRNA synthetases for translational and nontranslational functions. METHODS[J]. 2017, 113: 83-90, http://dx.doi.org/10.1016/j.ymeth.2016.11.014.
[5] Wang, Jing, Fang, Pengfei, Chase, Peter, Tshori, Sagi, Razin, Ehud, Spicer, Timothy P, Scampavia, Louis, Hodder, Peter, Guo, Min. Development of an HTS-Compatible Assay for Discovery of Melanoma-Related Microphthalmia Transcription Factor Disruptors Using AlphaScreen Technology. SLAS DISCOVERY[J]. 2017, 22(1): 58-66, https://www.webofscience.com/wos/woscc/full-record/WOS:000394206000007.
[6] Xing, Li, Zhu, Yuwei, Fang, Pengfei, Wang, Jing, Zeng, Fuxing, Li, Xuesong, Teng, Maikun, Li, Xu. Crystallization and preliminary crystallographic studies of UbiG, an O-methyltransferase from Escherichia coli. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS[J]. 2011, 67: 727-729, https://www.webofscience.com/wos/woscc/full-record/WOS:000291216800023.
[7] Fang, Pengfei, Li, Xu, Wang, Jing, Xing, Li, Gao, Yan, Niu, Liwen, Teng, Maikun. Crystal Structure of the Protein l-Isoaspartyl Methyltransferase from Escherichia coli. CELL BIOCHEMISTRY AND BIOPHYSICS[J]. 2010, 58(3): 163-167, https://www.webofscience.com/wos/woscc/full-record/WOS:000283081600008.
[8] Fang, Pengfei, Li, Xu, Wang, Jing, Niu, Liwen, Teng, Maikun. Structural Basis for the Specificity of the GAE Domain of yGGA2 for Its Accessory Proteins Ent3 and Ent5. BIOCHEMISTRY[J]. 2010, 49(36): 7949-7955, https://www.webofscience.com/wos/woscc/full-record/WOS:000281471600021.
[9] Fang, Pengfei, Wang, Jing, Li, Xu, Guo, Min, Xing, Li, Cao, Xu, Zhu, Yi, Gao, Yan, Niu, Liwen, Teng, Maikun. Crystallization and preliminary X-ray analysis of Escherichia coli RNase G. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS[J]. 2009, 65: 586-588, https://www.webofscience.com/wos/woscc/full-record/WOS:000266452100011.

