徐慧穎(華東理工大學生物工程學院副教授)

徐慧穎(華東理工大學生物工程學院副教授)

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徐慧穎,副教授,華東理工大學生物工程學院碩士生導師。

基本介紹

人物經歷,研究方向,代表性論文,

人物經歷

2010年6月畢業於河南師範大學生命科學學院,獲理學學士。2016年6月畢業於復旦大學化學系,獲理學博士學位。隨後進入華東理工大學生物工程學院從事師資博士後研究工作,合作導師葉邦策教授。2018年11月留校任教。

研究方向

1. 納米生物分析技術及微流控生物感測系統的開發。利用微流控技術的優勢以及功能納米材料和功能核酸的優良特性,構建可用於疾病標誌物分析的感測技術及食品安全分析技術。
2. 外泌體調控機理研究及其功能化套用。利用外泌體免疫原性低、運輸效率高、穩定性好等優勢,對其進行功能化修飾,用於藥物遞送及疾病治療。

代表性論文

1. Lu Zheng, Hua Wang, Peng Zuo, Yueling Liu, Huiying Xu*, and Bang-Ce Ye*. Rapid on-chip isolation of cancer-associated exosomes and combined analysis of exosomes and exosomal proteins. Analytical Chemistry,2022, 94, 7703.
2. Shifu Liang, Huiying Xu*, and Bang-Ce Ye*. Membrane-decorated exosomes for combination drug delivery and improved glioma therapy.Langmuir, 2022, 38, 299.
3. Huiying Xu, Chong Liao, Shifu Liang, Bang-Ce Ye*. A novel peptide-equipped exosomes platform for delivery of antisense oligonucleotides. ACS Applied Materials & Interfaces, 2021, 13, 10760.
4. Huiying Xu, Lu Zheng, Yu Zhou, Bang-Ce Ye*; An artificial enzyme cascade amplification strategy for highly sensitive and specific detection of breast cancer-derived exosomes, Analyst, 2021, 146, 5542.
5. Yu Zhou, Huiying Xu*, Hua Wang, and Bang-Ce Ye*. Detection of breast cancer-derived exosomes using the horseradish peroxidase-mimicking DNAzyme as an aptasensor. Analyst, 2020, 145, 107.
6. Huiying Xu, Bang-Ce Ye*. Advances in biosensing technologies for analysis of cancer-derived exosomes. Trends in Analytical Chemistry,2020, 123, 115773.
7. Huiying Xu, Chong Liao, Peng Zuo, Ziwen Liu, and Bang-Ce Ye*. A magnetic-based microfluidic device for on-chip isolation and detection of tumor-derived exosomes. Analytical Chemistry, 2018, 90, 13451.
8. Huiying Xu, Chong Liao, Yujie Liu, Bang-Ce Ye*, and Baohong Liu*. Iron phthalocyanine decorated nitrogen-doped graphene biosensing platform for real-time detection of nitric oxide released from living cells. Analytical Chemistry, 2018, 90, 4438.
9. Huiying Xu, Fenghua Geng, Xiangyu Jiang, Congying Shao, Yongxiang Wang*, Kefeng Wang, Peng Qu, Maotian Xu, and Bang-Ce Ye*. Design of metal-ion-triggered assembly of label-free split G-quadruplex/duplex DNA for turn-on detection of Hg in fetal calf serum. Sensors and Actuators B: Chemical, 2018, 255, 1024.
10. Huiying Xu, Jingjing Xiao, Baohong Liu*, Sophie Griveau, and Fethi Bedioui. Enhanced electrochemical sensing of thiols based on cobalt phthalocyanine immobilized on nitrogen-doped graphene. Biosensors and Bioelectronics, 2014, 66, 438.
11. Huiying Xu, Fenghua Geng, Yongxiang Wang,* Maotian Xu, Xinhe Lai, Peng Qu, Yintang Zhang, and Baohong Liu*. A label-free fluorescent molecular switch for a DNA hybridization assay utilizing a G-quadruplex selective auramine. Chemical Communications, 2015, 51, 8622.
12. Huiying Xu, Jingjing Xiao, Ling Yan, Lina Zhu, and Baohong Liu*. An electrochemical sensor for selective detection of dopamine based on nickel tetrasulfonated phthalocyanine functionalized nitrogen-doped graphene nanocomposites. Journal of Electroanalytical Chemistry, 2016, 779, 92.

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