徐功

徐功,男,1984年生,河南新野人,西北農林科技大學教授,博士生導師。

基本介紹

  • 中文名:徐功
  • 國籍:中國
  • 民族:漢
  • 出生地:河南新野
  • 出生日期:1984年
  • 畢業院校:瑞士伯爾尼大學
  • 學位/學歷:博士
  • 職業:教師
  • 專業方向:天然產物合成及綠色農藥創製
  • 任職院校:西北農林科技大學
人物經歷,教育科研,代表論文,

人物經歷

2007年本科畢業於鄭州大學化學系化學專業,獲理學學士學位,同年被保送到本校攻讀碩士學位,專業是藥物化學,師從劉宏民教授。獲得理學碩士學位後,2011年1月至2015年6月,在瑞士伯爾尼大學Philippe Renaud教授研究小組從事硼化學及自由基化學的研究,獲得化學與分子科學專業博士學位。2015年11月至2017年10月,在美國加州大學伯克利分校Thomas J. Maimone教授研究小組從事複雜活性天然萜類化合物的全合成研究。2018年3月至今,在西北農林科技大學植物保護學院農藥學系從事教學和科研工作。

教育科研

研究方向:1. 天然產物全合成與結構修飾;2. 綠色農藥分子的設計與合成;3. 農藥分子的靶標發現與作用機制研究
科研項目:先後主持國家自然科學基金青年項目、陝西省重點研發計畫、國家自然科學基金面上項目
教學工作:儀器分析、藥物合成、農藥研發策略與技術進展、現代農藥分子設計原理及方法

代表論文

1. Gong Xu, Philippe Renaud*, Intramolecular Cyclopropanation of 1,4-Dienes through Hydroboration–Homologation: Easy Access to Bicyclo[3.1.0]hexanes, Angew. Chem. Int. Ed. 2016, 55 (11), 3657–3661.
2. Chi P. Ting, Gong Xu,Xianhuang Zeng, Thomas J. Maimone*, Annulative Methods Enable a Total Synthesis of the Complex Meroterpene Berkeleyone A, J. Am. Chem. Soc. 2016, 138 (45), 14868–14871. (contributed equally) (Highlighted by Erick M. Carreira, Johannes Boshkow, Synfacts, 2017, 13(2), 125.)
3. Gong Xu, Masha Elkin, Dean J. Tantillo, Timothy R. Newhouse*, Thomas J. Maimone*, Traversing Biosynthetic Carbocation Landscapes in the Total Synthesis of Andrastin and Terretonin Meroterpenes, Angew. Chem. Int. Ed. 2017, 56 (41), 12498–12502.
4. Xinyue Chen, Danyang Zhang, Dan Xu, Huan Zhou, Gong Xu*, Remote C–H Activation Strategy Enables Total Syntheses of Nortriterpenoids (±)-Walsucochin B and (±)-Walsucochinoids M and N, Org. Lett. 2020, 22 (17), 6993–6997. (Highlighted by Erick M. Carreira, Viktoria C. Gerken, Synfacts, 2020, 16 (11), 1261.)
5. Wei Wang, Shan Zhang,Jianhua Wang, Furan Wu, Tao Wang*, Gong Xu*, Bioactivity-Guided Synthesis Accelerates the Discovery of 3‑(Iso)quinolinyl-4-chromenones as Potent Fungicide Candidates, J. Agric. Food Chem. 2021, 69 (1), 491−500.
6. Wei Wang, Jianhua Wang, Furan Wu, Huan Zhou, Dan Xu*, Gong Xu*, Synthesis and Biological Activity of Novel Pyrazol-5-yl-benzamide Derivatives as Potential Succinate Dehydrogenase Inhibitors, J. Agric. Food Chem. 2021, 69 (20), 5746-5754.
7. Wei Wang, Jianhua Wang, Jipeng Wu, Mengyun Jin, Junling Li, Shiyang Jin, Wangxiang Li, Dan Xu*, Xili Liu, Gong Xu*, Rational Design, Synthesis, and Biological Evaluation of Fluorine- and Chlorine-Substituted Pyrazol-5-yl-benzamide Derivatives as Potential Succinate Dehydrogenase Inhibitors, J. Agric. Food Chem. 2022, 70 (24), 7566–7575.
8. Hong-Wei He, Fei-Yu Wang, Danyang Zhang, Cai-Yun Chen, Dan Xu, Huan Zhou*, Xili Liu, Gong Xu*, Discovery of Novel α-Methylene-γ-Butyrolactone Derivatives Containing Vanillin Moieties as Antiviral and Antifungal Agents, J. Agric. Food Chem. 2022, 70 (33), 10316–10325.
9. Wen-Bo Han*, Yi-Jie Zhai, Rong Zhang, Xu-Shun Gong, Jia-Qian Li, Gong Xu*, Xinxiang Lei, Liangcheng Du, Jin-Ming Gao*, Tricrilactones A–H, Potent Antiosteoporosis Macrolides with Distinctive Ring Skeletons from Trichocladium crispatum, an Alpine Moss-Associated Fungus, Angew. Chem. Int. Ed. 2023, 62, e2023007.
10. Yuan Chi, Hong-Wei He, Cai-Yun Chen, Si-Ying Zhao, Huan Zhou, Dan Xu, Xili Liu, Gong Xu*, Furofuran Lignans for Plant Protection: Discovery of Sesamolin and Its Derivatives as Novel Anti-Tobacco Mosaic Virus and Antibacterial Agents, J. Agric. Food Chem. 2023, 71 (28), 10798-10808.
11. Hong-Wei He, Dan Xu, Ke-Huan Wu, Zheng-Yi Lu, Xili Liu, Gong Xu*, Discovery of Novel Salicylaldehyde Derivatives Incorporating an α-Methylene-γ-Butyrolactone Moiety as Fungicidal Agents, Pest. Manag. Sci. 2023, doi.org/10.1002/ps.7703.

相關詞條

熱門詞條

聯絡我們