張亞霖，男，博士，廈門大學生命科學學院教授，博士生導師。
基本介紹
- 中文名：張亞霖
- 畢業院校：廈門大學
- 學位/學歷：博士
- 職業：教師
- 專業方向：代謝紊亂與神經退行性疾病的發生髮展密切相關
- 任職院校：廈門大學生命科學學院
人物經歷,研究方向,學術成果,
人物經歷
2008年，廈門大學，生物科學專業，學士學位
2013年，廈門大學，生物化學與分子生物學專業，博士學位
2014-2018年，美國愛因斯坦醫學院博士後
2018年至今，廈門大學生命科學學院教授
2008, B.Sc., Biological Sciences, Xiamen University
2013, Ph.D., Biochemistry and Molecular Biology, Xiamen University
2014-2018, Postdoctoral Fellow, Albert Einstein College of Medicine
2018-Present, Professor, School of Life Sciences, Xiamen University
研究方向
代謝紊亂與神經退行性疾病的發生髮展密切相關
學術成果
1.Zhang Y, Kim MS, Jia B, Yan J, Zuniga-Hertz JP, Han C, Cai D. Hypothalamic stem cells control aging speed partly through exosomal miRNAs.Nature. 2017 Aug 3;548(7665):52-57.
2.Zhang Y, Reichel JM, Han C, Zuniga-Hertz JP, Cai D. Astrocytic process plasticity andIKKβ/NF-κB in central control of blood glucose, blood pressure and body weight.CellMetabolism. 2017 May 2;25(5):1091-1102.
3.Ale A,Zhang Y, Han C, Cai D. Obesity-associated extracellular mtDNA activates central TGFβ pathway to cause blood pressure increase.Am J Physiol Endocrinol Metab. 2016 Nov 15:ajpendo.00337.2016.
4.Kim MS, Yan J, Wu W, Zhang G,Zhang Y, Cai D. Rapid linkage of innate immunological signals to adaptive immunity by the brain-fat axis.Nature Immunology. 2015 May;16(5):525-33.
5.Zhang Y, Liu G, Yan J,Zhang Y,Li B, Cai D. Metabolic learning and memory formation by the brain influence systemic metabolic homeostasis.Nature Communications. 2015 Apr 7;6:6704.
6.Zhang CS, Jiang B, Li M, Zhu M, Peng Y,Zhang Y, Wu YQ, Li TY, Liang Y, Lu Z, Lian G, Liu Q, Guo H, Yin Z, Ye Z, Han J, Wu JW, Yin H, Lin SY, Lin SC. The lysosomal v-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism.Cell Metabolism. 2014 Sep 2;20(3):526-40.
7.Zhang Y, Guo H, Zhang CS, Lin SY, Yin Z, Peng Y, Luo H, Shi Y, Lian G, Zhang C, Li M, Ye Z, Ye J, Han J, Li P, Wu JW, Lin SC. AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation.Cell Metabolism. 2013 Oct 1;18(4):546-55.
