基本介紹
- 中文名稱：宋建國
- 職業：醫生
- 專業：細胞分化與凋亡
- 學歷：博士
- 教學職稱：博導
個人簡介,個人事跡,
個人簡介
個人事跡
細胞增殖、凋亡和分化的信號傳導機制。主要研究轉化生長因子-beta在細胞增殖、凋亡和分化過程中的不同生物學效應及其相關的機制，包括其他因素或信號分子對轉化生長因子-beta介導的生物學效應的調節作用。
發表論文：
1.Y Yang, X Pan, W Lei, J Wang and J Song Transforming growth factor-beta1 induces epithelial-to-mesenchymal transition and apoptosis via a cell cycle-dependent mechanism （2006）Oncogene 25:7235-44
2.Yanan Yang, Xinchao Pan, Weiwei Lei, Jun Wang, Jian Shi, Fuqiang Li and Jianguo Song (2006) Regulation of Transforming Growth Factor-1-Induced Apoptosis and Epithelial-to-Mesenchymal Transition by Protein Kinase A and Signal Transducers and Activators of Transcription 3 Cancer Res 66:8617-24
3.Yiran Zhou, Dongmei Wang, Fuqiang Li, Jian Shi and Jianguo Song Different roles of protein kinase C-betaI and -delta in the regulation of adipocyte differentiation （2006） Int J Biochem Cell Biol 38:2151-63.
4，Bo Zhou, Fuqiang Li, Hehua Chen and Jianguo Song The modulation of apoptosis by cyclic AMP involves Akt and epidermal growth factor receptor （2005）Int J Biochem Cell Biol.37:1483-95
5.Sheng Zhao, Yanan Yang and Jianguo Song (2004). Ceramide induces caspase-dependent and -independent apoptosis in A-431 cells. J. Cell. Physiol. 199:47-56.
6.Yanan Yang, Sheng Zhao, and Jianguo Song （2004）. Caspase-dependent apoptosis and -independent poly(ADP-ribose) polymerase cleavage induced by transforming growth factor-?1. Int. J. Biochem. Cell Biol. 36:223-34
7.He-Hua Chen, Sheng Zhao and Jian-Guo Song (2003). TGF-?1 suppresses apoptosis via differential regulation of MAP kinases and ceramide production. Cell Death and Differentiation 10:320-331.
8.Zhao S, Du X, Chen J, Zhou Y, Song J (2002). Secretory phospholipase A2 inhibits epidermal growth factor-induced receptor activation. Exp. Cell Res. 279:354-365.
9.Sheng Zhao, Xiao-Yan Du, Min-Qiang Chai, Jun-Song Chen, Yuan-Chong Zhou and Jian-Guo Song （2002）.Secretory phospholipase A2 induces apoptosis via a mechanism involving ceramide generation. BBA-Mol Biol Cell Lipids. 1581:75-88.
10.Chai Min-Qiang, Chen Jun-Song, Zhao Sheng, Song Jian-Guo (2001). Propranolol increases phosphatidic acid level via phospholipase D activation. Acta Pharmacologica Sinica. 22 22:777-784.
11.Jinhui Liao, Junsong Chen, Minqiang Chai, Sheng Zhao, and Jianguo Song (2001). The involvement of p38 MAPK in transforming growth factor beta 1-induced apoptosis in murine hepatocytes. Cell Research, 11:89-94.
12.Junsong Chen and Jianguo Song (2001). Bradykinin induces protein kinase C-dependent activation of phospholipase D in A-431 cells. IUBMB Life, 51:49-56.
13.Binghong Zhou, Junsong Chen, Mingqiang Chai, Sheng Zhao, Jun Lian, Hehua Chen, and Jianguo Song (2000). Activation of phospholipase D activity in transforming growth factor-beta-induced cell growth inhibition. Cell Research, 10:139-149.
14.Jun-Song Chen, Min-Qiang Chai, He-Hua Chen, Sheng Zhao and Jian-Guo Song (2000). Regulation of phospholipase D activity and ceramide production in daunorubicin-induced apoptosis in A-431 cells. BBA-Mol Biol Cell Lipids. 1488:219-232.
