人物經歷
2004年7月畢業於河北醫科大學研究生學院腫瘤學專業,留校於河北醫科大學第四醫院腫瘤內科工作,2023年9月開始在
河北醫科大學第一醫院工作至今。2017年以醫學訪問學者身份赴澳訪學半年。
研究方向
從事腫瘤內科工作20餘年,在常見惡性腫瘤,包括乳腺癌、肺癌、消化道腫瘤等診治方面具有豐富的臨床經驗。
著作譯作
參編著作7部。
科研成果
研課5項,科研經費55萬元,參與多項國際國內GCP研究,包括I期II期III期以及上市後IV期和真實世界研究。以第一作者或通訊作者發表論文14篇,其中SCI論文7篇;北圖核心論文4篇;科技核心3篇。
(1) Lv Y, Bai Z, Wang X, et al. Comprehensive evaluation of breast cancer immunotherapy and tumor microenvironment characterization based on interleukin genes-related risk model. Sci Rep. 2022;12(1):20524. Published 2022 Nov 28. doi:10.1038/s41598-022-25059-8.
(2) Lv Y, Shan Y, Song L, et al. Type I collagen promotes tumor progression of integrin β1 positive gast-ric cancer through a BCL9L/β-catenin signaling pathway. Aging (Albany NY). 2021;13(14):19064-19076. doi:10.18632/aging.20335.
(3) Lv Y, Xu M, Sun Y, et al. Prognostic significance of excision repair cross complementation group 1 rs2298881 in patients with gastric cancer receiving platinum-based chemotherapy: A PRISMA-compliant meta-analysis. Medicine (Baltimore). 2021;100(33):e26850. doi:10.1097/MD.0000000000026850.
(4) Lye, Y. L., Shan, B., Jia, C. H., Liu, J., Hou, J., Du, W. L., Feng, R., & Liang, P. (2023). Toxic Epidermal Necrolysis Induced by Sintilimab: A Case Report. Annals of dermatology, 35(Suppl 1), S100–S102. https://doi.org/10.5021/ad.21.072.
(5) Liang, P., Zhu, M. Y., Yang, R., Wang, X., Yue, H., Zheng, Y., Liu, J., Lv, Y. L., & Shan, B. (2025). O-bese patients with malignant tumor: a case series and literature review. Discover oncology, 16(1), 1020. https://doi.org/10.1007/s12672-025-02689-8,第一通訊.
(6) Zhang, X., Lin, J., Xu, H., Zhou, Y., Mu, Z., Shi, R., & Lv, Y. (2025). Mechanism of action and therap-eutic value of anoctamin-1 in gastrointestinal cancers. Frontiers in immunology, 16, 1599100. https://doi.org/10.3389/fimmu.2025.1599100,第一通訊.
(7)Lv Y, Song L, Chang L, Zhang X, Liu Y, Liu W. Effect of bevacizumab combined with chemotherapy at different sequences in the gastric-cancer-bearing nude mice. Journal of cancer research and therapeutics, 2018;14(Supplement):S190-S196. doi:10.4103/0973-1482.171364.
(8)Lv Y, Song L, Chang L, et al. Inhibitory effects of bevacizumab monoclonal antibodies in combina-tion with chemotherapy in different time sequences on a human gastric carcinoma cell line. Irish journal of medical science, 2017;186(2):275-280. doi:10.1007/s11845-016-1471-1.
(9)Lv Y, Song L, Chang L, et al. Bevacizumab followed by chemotherapy is potential therapy for gast-ric cancer. J BUON. 2016;21(6):1466-1470.
(10)單玉潔,楊天宇,王星涵,呂雅蕾. 臍尿管癌患者基因檢測下的個體化治療1例[J]. 中國腫瘤臨床,2021,48(23):1241-1242. DOI:10.12354/j.issn.1000-8179.2021.20211417.
獲獎情況
獲省級科技進步獎2項;市廳級科技進步獎2項;2022年榮獲河北省第二屆住院醫師規範化培訓教學查房競賽內科專業二等獎;2021河北抗癌協會年會論文三等獎;