吳兆鵬(科竟達生物科技有限公司執行長)

吳兆鵬(科竟達生物科技有限公司執行長)

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吳兆鵬,男,漢族,1977年12月出生,廣東江門人,2010年博士畢業於香港城市大學套用物理及材料科學系,其後留校參與多項表面等離子共振生物感測器(Surface Plasmon Resonance Biosensor)相關的科研工作並擔任博士後研究員至2018年。

2018年10月吳博士主導的量子激元生物晶片感測器(Quantum Plasmonic Lab-on-Chip Biosensor)項目獲得香港天使投資人青睞,共同創立科竟達生物科技有限公司,現任公司執行長。

基本介紹

  • 中文名:吳兆鵬
  • 外文名:NG SIU PANG 
  • 國籍中國
  • 民族:漢族
  • 籍貫:廣東江門
  • 畢業院校:香港城市大學 
  • 職務:科竟達生物科技有限公司執行長
  • 性別:男
人物履歷,人物經歷,論文著作,專利文書,

人物履歷

2003年,畢業於香港理工大學並取得科學學士學位;
2007年,在香港城市大學(CityU HK) 洪友仁教授指導下獲得雷射散斑剪下(Shearogrphy)的無損檢測光學計量哲學碩士學位;
2008年,開始在無標記表面電漿共振(SPR)光學生物感測器方面的研究,在物理和材料科學系胡志文教授的監督下展開科研工作。在連續兩年的博士學位期間,發明了具有寬動態測量範圍的超靈敏無標籤表面電漿共振(SPR)生物感測器的白光光譜干涉技術和表面電漿增強染料敏化太陽能電池,因此獲得4項美國專利和2項中國發明專利;
自2010年畢業後,在城市大學擔任研究員職位,並繼續致力於開發無標籤光學生物感測器的各種套用。最新的進展包括:(1)用新型氮化鈦薄膜代替常規金材料用於SPR生物感測器,(2)快速檢測飲用水中痕量鉛(II)離子無標記LSPR光化學感測器技術,使其檢測極限為世界衛生組織指標閾值的1/1000,(3)使用自組裝Gold Nanoislands LSPR生物感測器直接檢測腫瘤細胞來源的外泌體,並區分外泌體(exosome)和微囊泡 (micro-vesicles)。因此,在生物感測器,光學和分析化學領域的高影響力期刊中發表/共同撰寫了超過80篇論文和10多個發明專利。最近,還參與了量子化學計算的研究工作,利用密度泛函理論和基於第一性原理的分子動力學來進一步闡明生物感測機制;
2018年10月,吳兆鵬博士與聯合創始人創立科竟達生物科技有限公司,其目標是推廣免標籤量子激元共振生物晶片感測器(QPLoC)在醫學臨床套用。

人物經歷

2023年4月,參加瑞士蘇黎世舉行的第14屆微流控聯盟會議(Microfluidics Consortium 14),到訪蘇黎世聯邦理工大學。
2024年6月,代表公司捐贈一套QPLoC 系統與香港都會大學,推動香港本地大學的臨床蛋白質組學的科學研究。
2024年8月,以“量子激元生物感測器”為題,參加廣州市衛健委組織的“2024第二屆臨床研究機構展暨廣州臨床研究產業交易會”。

論文著作

(1)Chen Xu, Guangyu Qiu, Siu Pang Ng, Chi-Man Lawrence Wu: Nanostructured titanium nitride for highly sensitive localized surface plasmon resonance biosensing. Ceramics International 25-May-2020.
(2)Abhimanyu Thakur, Guangyu Qiu, Xu, Chen Xu, X. Han, T. Yang; Siu Pang Ng; KWY. Chan, Chi-Man Lawrence Wu, Youngjin Lee: Label-free sensing of exosomal MCT1 and CD147 for tracking metabolic reprogramming and malignant progression in glioma Science Advances 6, 26, eaaz6119, 2020.
(3)Guangyu Qiu, Abhimanyu Thakur, Chen Xu, Siu Pang Ng, Youngjin Lee, Chi-Man Lawrence Wu: Detection of Glioma‐Derived Exosomes with the Biotinylated Antibody‐Functionalized Titanium Nitride Plasmonic Biosensor. Advanced Functional Materials 29, 9, 2019.
(4)Guangyu Qiu, Siu Pang Ng, Chi-Man Lawrence Wu: Bimetallic Au-Ag Alloy Nanoislands for Highly Sensitive Localized Surface Plasmon Resonance Biosensing. Sensors and Actuators B Chemical 03/2018.
(5)Guangyu Qiu, Siu Pang Ng, Chi-Man Lawrence Wu: Label-free Surface Plasmon Resonance Biosensing with Titanium Nitride Thin film. Biosensors & Bioelectronics 02/2018; 106.
(6)Abhimanyu Thakur, Guangyu Qiu, Siu-Pang NG, Chi-Man Lawrence Wu, Youngjin Lee: Detection of membrane antigens of extracellular vesicles by surface plasmon resonance.
(7)Abhimanyu Thakur, Guangyu Qiu, Siu-Pang NG, Guan Jintao, Jianbo Yue, Youngjin Lee, Chi-Man Lawrence Wu: Direct detection of two different tumor-derived extracellular vesicles by SAM-AuNIs LSPR biosensor. Biosensors & Bioelectronics 04/2017.
(8)Guangyu Qiu, Siu Pang Ng, Xiongyi Liang, Ning Ding, Xiangfeng Chen, Chi-Man Lawrence Wu: Label-free LSPR Detection of Trace Lead(II) Ions in Drinking Water by Synthetic Poly(mPD-co-ASA) Nanoparticles on Gold Nanoislands. Analytical Chemistry 02/2017; 89(3).
(9)Siu Pang Ng, Guangyu Qiu, Ning Ding, Xiaoqing Lu, Chi-Man Lawrence Wu: Label-free detection of 3-nitro-L-tyrosine with nickel doped graphene localized surface plasmon resonance biosensor. Biosensors & Bioelectronics 05/2016; 89(Pt 1).
(10)Guangyu Qiu, Siu Pang Ng, Chi-Man Lawrence Wu: Dielectric functionalization for differential phase detecting localized surface plasmon resonance biosensor. Sensors and Actuators B Chemical 04/2016.
(11)Siu Pang Ng, Guangyu Qiu, Chi-Man Lawrence Wu: Differential phase-detecting localized surface plasmon resonance sensor with self-assembly gold nanoislands. Optics Letters 05/2015; 40(9):1924.
(12)Siu Pang Ng, Yan-Yi Yip, Chi-Man Lawrence Wu: Biosensing with Gain-assisted Surface Plasmon-Polariton Amplifier: A Computational Investigation. Sensors and Actuators B Chemical 04/2015;
(13)Fong-Chuen Loo, Siu-Pang Ng, Chi-Man Lawrence Wu, Siu Kai Kong: An aptasensor using DNA aptamer and white light common-path SPR spectral interferometry to detect cytochrome-c for anti-cancer drug screening. Sensors and Actuators B Chemical 03/2014; 198:416.
(14)Siu-Pang Ng, XiaoQing Lu, Ning Ding, Chi-Man Lawrence Wu, Chun-Sing Lee: Plasmonic enhanced dye-sensitized solar cells with self-assembly gold-TiO2@core–shell nanoislands. Solar Energy 01/2014; 99:115–125.
(15)Chi-Man Lawrence Wu, Siu-Pang Ng: Self-assembly Gold Nanoislands for Localized Surface Plasmon Resonance Biosensing. MRS Online Proceeding Library Archive 11/2013; 1566(1).
(16)Siu Pang Ng, Fong Chuen Loo, Shu Yuen Wu, Siu Kai Kong, Chi Man Lawrence Wu, Ho Pui Ho: Common-path spectral interferometry with temporal carrier for highly sensitive surface plasmon resonance sensing. Optics Express 08/2013; 21(17):20268-20273.
(17)Siu-Pang Ng, Chi-Man Lawrence Wu, Shu-Yuen Wu, Ho-Pui Ho, Siu-Kai Kong: Surface Plasmon Resonance Biosensing via Differential Spectral Phase Interferometry. Proceedings of SPIE - The International Society for Optical Engineering 02/2011; 7911.
(18)Siu Pang Ng, Chi Man Lawrence Wu, Shu Yuen Wu, Ho Pui Ho: White-light spectral interferometry for surface plasmon resonance sensing applications. Optics Express 02/2011; 19(5):4521-7.
(19)Siu-Pang Ng, Chi-Man Lawrence Wu, Shu-Yuen Wu, Ho-Pui Ho, S.K. Kong: Differential spectral phase interferometry for wide dynamic range surface plasmon resonance biosensing. Biosensors & Bioelectronics 12/2010; 26(4):1593-8.

專利文書

(1)吳兆鵬,一種用於檢測新型冠狀病毒的CRISPR-Cas13系統及其試劑盒和方法,中國發明專利授權號CN 116042927 B
(2)吳兆鵬,一種光波導、其製造方法、包含其的生物感測系統及其套用,中國發明專利授權號 CN 112033931 B
(3)吳兆鵬,一種局域表面電漿共振生物感測裝置,中國發明專利授權號CN 115356300 B
(4)吳兆鵬,熾熱表面電漿共振生物晶片、其製造方法、包含其的生物感測系統及其套用,中國發明專利授權號 CN 115290605 B
(5)吳兆鵬,一種在聚合物光波導表面裝飾納米立方體的方法、由其製造的光波導、生物感測系統及套用,中國發明專利授權號CN 112014924 B
(6)吳兆鵬,一種局域表面電漿激元共振生物晶片、其製造方法、包含其的生物感測系統及其套用, 中國發明專利授權號CN 112033932 B
(7)吳兆鵬,聚合物用作生物晶片的基底的用途, 中國發明專利授權號CN 111999784 B
(8)Siu Pang Ng, Chi-Man Lawrence Wu, Chen Xu; Guangyu Qiu: 襯底上形成具有間隙電漿納米材料的方法, 感測器, 中國發明專利申請號CN 112240877 A
(9)Youngjin LEE, Abhimanyu Thakur, Chi-man Lawrence Wu, Guangyu Qiu, Chen Xu, Siu-pang Ng, Tian Yang: Methods and kits for detecting exosomal protein. Ref. No: US20210373022A1, Year: 06/2020
(10)Youngjin LEE, Abhimanyu Thakur, Chi-man Lawrence Wu, Chen Xu, Siu-pang Ng, Sensor for liquid biopsy and its method of making, and method of non-invasive liquid biopsy. Ref. No: US12092636B2, Year: 09/2024
(11)Siu Pang Ng, Chi-Man Lawrence Wu, Guangyu QIU, Hui Lun Anton Law: Optochemical detector and a method for fabricating an optochemical detector. Ref. No: US 10677790B2, Year: 06/2020
(12)Ho Pui Ho, Shu Yuen Wu, Chi-man Lawrence Wu, Siu Pang Ng, Siu Kai Kong: Optical sensing apparatus and a method for detecting characteristics of a sample. Ref. No: US 9322778B2, Year: 04/2016
(13)Siu Pang Ng, Chi-man Lawrence Wu, Chun-sing Lee: Plasmonic enhanced tandem dye-sensitized solar cell with metallic nanostrucutres. Ref. No: US9287057B2, Year: 03/2016
(14)Lawrence Chi-man Wu, Siu pang Ng, Ho Pui Ho, Shu Yuen Wu: Optical sensing devices and methods for detecting samples using the same. Ref. No: US8988688B2, Year: 03/2015
(15)Shu Yuen Wu, Ho Pui Ho, C.M.Lawrence Wu, Siu Pang Ng: Optical Sensing devices and methods for detecting samples using the same. Ref. No: US8953168B2, Year: 02/2015

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