fumarase,英語單詞,主要用作名詞,作名詞時譯為“[生化] 延胡索酸酶”。
基本介紹
- 外文名:fumarase
- 詞性:名詞
- 發音:['fju:məreis]
- 釋義:[生化] 延胡索酸酶

fumarase,英語單詞,主要用作名詞,作名詞時譯為“[生化] 延胡索酸酶”。
延胡索酸酶(反丁烯二酸酶)fumarase 正式名稱為延胡索酸水化酶(fumarate hydra-tase),是催化延胡索酸+H2O→L-蘋果酸可逆進行相互轉變反應的酶, EC4.2.1.2.最適 pH=6.5-8.0。底物特異性非常嚴格,反應平衡偏右,生物界中廣泛發現,可從肝臟、心肌、骨骼肌中提純,從心肌中提純結晶化的延胡索酸酶分子...
延胡索酸酶(fumarase)(延胡索酸水化酶(fumaratehydratase))通過將H2Otrans立體特異添加到延胡索酸雙鍵上,催化延胡索酸水化生成L-蘋果酸,反應是可逆的。延胡索酸也象檸檬酸一樣是一個前手性分子,當延胡羧酸被定位在酶的活性部位時,底物的雙鍵只受到來自一個方向的攻擊。循環閉環 蘋果酸脫氫酶催化蘋果酸氧化重新...
其他碳源如葡萄糖、 乳酸、乳糖等發酵產物都為丙乙酸的混和物。平衡:CH3COCOOH+4H-→CH3CH2COOH+H2O (1)methylmalony-CoA Coboxytransferase (2)malate dehydrogense (3)fumarase (4)succinate dehydrogenase (5)proptonate dehydrogenase (6)methylmalonyl-CoA mutase (7)methylmalonyl-CoA racemase ...
[13] Usa K, Liu Y, Geurts AM, Cheng Y, Lazar J, Baker MA, Grzybowski M, He Y, Tian Z*, Liang M*. Elevation of fumarase attenuates hypertension and can result from a nonsynonymous sequence variation or increased expression depending on rat strain. Physiol Genomics. 2017 Sep 1;49(9):...
Wang T, Yu Q, Li J, Hu B, Zhao Q, Ma C, Huang W, Zhuo L, Fang H, Liao L, Eugene Chin Y, Jiang Y. O-GlcNAcylation of fumarase maintains tumour growth under glucose deficiency. Nat Cell Biol. 2017, 19(7):833-843. PMID:28628081 Wei W, Mao A, Tang B, Zeng Q, Gao S, ...
[30]Chen, Z., Zhou, Q. andGe, R.*(2012) Inhibition of fumarase by bismuth(III): implications for the tricarboxylic acid cycle as a potential target of bismuth drugs inHelicobacter pylori. Biometals 25, 95-102;[31]葛瑞光(2012)第五章蛋白質體外研究—結構與功能,《功能蛋白研究》,科學...
12.Marconi, W.,Faiola, F. &Piozzi, A.Catalytic activity of immobilized fumarase.Journal of MolecularCatalysis. B, Enzymatic1-3, 93-99 (2001).13.Costa, Y., Ding, J., Theunissen, T.W.,Faiola, F., Hore, T.A., Shliaha, P.V., Fidalgo, M., Saunders, A., Lawrance, M., Diet...
2. Song Ping, Li Shuang, Ding Yueyue, Xu Qing and Huang He. Expression and characterization of fumarase (FUMR) from Rhizopus oryzae. Fungal Biology. 2011, 115(1): 49-53.3. Song Ping, Xu Xian, Jiang Ling, Zhang Rencuan, Wang Jing, Xu Qing and Li Shuang. Genome Sequence of ...
7 Jiang C, Wu LL, Zhao GC, Shen PH, Jin K, Hao ZY, Li SX, Ma GF, Luo FF, Hu GQ, Kang WL, Bi YL, Qin XM, Tang XL, Wu B. Identification and characterization of a novel fumarase gene by metagenome expression cloning from marine microorganisms. Microb Cell Fact, 2010, 9: 91....
