《Coagulation and Blood Transfusion 1990》是1991年出版的圖書，作者是Smit Sibinga, C. Th、Das, P. C.、Mannucci, P. M.。
基本介紹
- 外文名：Coagulation and Blood Transfusion 1990
- 作者：Smit Sibinga, C. Th、Das, P. C.、Mannucci, P. M.
- 出版時間：1991年9月
- 頁數：284 頁
- ISBN：9780792313311
- 定價：247.47 美元
內容簡介
While the enzyme cascade that allows coagulation is well known physiologically, its elegant practical examples are vividly demonstrable in the clinical application of blood and components for the treatment of bleeding problems in surgery, trauma or in congenital deficiency in patients. This volume provides the fundamental and recent understanding relating to coagulation pathways, recombinant technology and other methods for coagulation factor production, up to date laboratory assay, preservation of cellular and plasma components, and their clinical use in surgery and medicine, including the immuno response to repeated challenge to contaminating protein in coagulation factor concentrates. The interrelated but multi-disciplinary chapters have been integrated in four sections: Principles and Fundamentals: Mechanism of thrombin formation, structure-function relationship of coagulation proteins, role of calcium and anticoagulant, blood collection on haemostatic potential of plasma proteins and platelets; Factor VIII yields from anticoagulant exchanged plasma; Preservation Aspects: Platelet function preservation, platelet interaction with vessel wall, trends in the use of coagulation factor concentrate, immuno purification of Factor VIII, and structural and fundamental properties of recombinant coagulation factors; Laboratory Aspects: Platelets counting and function testing, platelet crossmatch predictive value, clinical efficacy of platelet concentrate, protein C and protein S, principle of coagulation factor assay, standardisation of clotting factor assays, and clinical efficacy of clotting factor concentrates.
