陳彥佐(華東理工大學藥學院副教授)

陳彥佐，女，博士，華東理工大學藥學院副教授、碩士生導師。

基本介紹

• 中文名：陳彥佐
• 畢業院校：復旦大學
• 學位/學歷：博士
• 職業：教師
• 專業方向：新型藥物傳遞系統的構建與評價
• 任職院校：華東理工大學

個人經歷

2013年畢業於復旦大學藥學院藥劑學專業，獲理學博士學位。同年9月加入華東理工大學藥學院，從事新型納米遞藥系統方向的博士後研究。2017年至2018年間在美國北卡羅來納大學教堂山分校Leaf Huang教授課題組進行腫瘤微環境和免疫機制方面研究。2018年9月晉升副教授，從事藥劑學相關的教學和科研工作。

研究方向

1.新型藥物傳遞系統的構建與評價

2.腫瘤聯合治療策略研究

3.藥物新劑型與新製劑的研究開發

學術成果

作為項目負責人，先後主持中國博士後基金，上海市博士後基金，國家自然科學基金青年基金，教育部基本科研業務費探索研究基金等科研項目6項，發表SCI科研論文30餘篇，申請中國發明專利3項，參與出版教材3冊。

代表性論文：

1.Yanzuo Chen, Wantong Song*, Limei Shen, Nasha Qiu, Mengying Hu, Yun Liu, Qi Liu, Leaf Huang*. Vasodilator hydralazine promotes nanoparticle penetration in advanced desmoplastic tumor.ACS Nano.2019;

2. Junru Wu, Shu Feng, Wenchao Liu, Feng Gao*,Yanzuo Chen*. Targeting integrin-rich tumors with temoporfin-loaded vitamin-E-succinate-grafted chitosan oligosaccharide/d-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles to enhance photodynamic therapy efficiency.Int. J. Pharm.2017;

3.Yanzuo Chen, Shu Feng, Wenchao Liu, Zeting Yuan, Peihao Yin, Feng Gao*. Vitamin E succinate-grafted-chitosan oligosaccharide/RGD-conjugated TPGS mixed micelles loaded with paclitaxel for U87MG tumor therapy.Mol. Pharm.2017;

4. Yukun Huang, Wenchao Liu, Feng Gao, Xiaoling Fang,Yanzuo Chen*. c(RGDyK)-decorated Pluronic micelles for enhanced doxorubicin and paclitaxel delivery to brain glioma.Int. J. Nanomedicine.2016;

5.Yanzuo Chen*, Wei Zhang, Yukun Huang, Feng Gao, Xiaoling Fang*. In vivo biodistribution and anti-tumor efficacy evaluation of doxorubicin and paclitaxel-loaded Pluronic micelles decorated with c(RGDyK) peptide.PLoS One.2016;

6.Yanzuo Chen, Yukun Huang, Dongdong Qin, Wenchao Liu, Chao Song, Kaiyan Lou*, Wei Wang, Feng Gao*. β-cyclodextrin based inclusion complexation bridged biodegradable self-assembly macromolecular micelle for the delivery of paclitaxel.PLoS One.2016;

7.Yanzuo Chen*,WeiZhang,YukunHuang,FengGao,XianyiSha,XiaolingFang*. Pluronic-based functional polymeric mixed micelles for co-delivery of doxorubicin and paclitaxel to multidrug resistant tumor.Int. J. Pharm.2015;

8.Yanzuo Chen*,WeiZhang,YukunHuang,FengGao,XianyiSha,KaiyanLou,XiaolingFang*. The therapeutic effect of methotrexate-conjugated Pluronic-based polymeric micelles on the folate receptor-rich tumors treatment.Int. J. Nanomedicine.2015

9.Yanzuo Chen*,WeiZhang,YukunHuang,FengGao,XiaolingFang*. Dual-functional c(RGDyK)-decorated Pluronic micelles designed for antiangiogenesis and the treatment of drug-resistant tumor.Int. J. Nanomedicine.2015;

10.Yanzuo Chen,YukunHuang, Yuan Chen, Yajing Ye, Kaiyan Lou, Feng Gao*. Novel nanoparticles composed of chitosan and β-cyclodextrin derivatives as potential insoluble drug carrier.Chin. Chem. Lett.2015;

11.Yanzuo Chen, Wuli Yang, Baisong Chang, Hangting Hu, Xiaoling Fang, Xianyi Sha*. In vivo distribution and antitumor activity of doxorubicin-loaded N-isopropylacrylamide-co-methacrylic acid coated mesoporous silica nanoparticles and safety evaluation.Eur. J. Pharm. Biopharm.2013;