趙書博，女，博士。現任吉林大學基礎醫學院副教授。
基本介紹
- 中文名：趙書博
- 國籍：中國
人物經歷,主要成就,科研成就,榮譽表彰,
人物經歷
2011.09-2015.06，東北師範大學，生物科學學士。
2015.09-2018.06，廈門大學，生物學碩士。
2018.10-2023.02，德國慕尼黑大學，生物化學博士。
2023.02-2024.01，德國慕尼黑大學化學與藥劑學學院博士後。
2024.02-2024.04，德國慕尼黑大學化學與藥劑學學院訪問學者。
2024.05- ，吉林大學基礎醫學院副教授。
主要成就
科研成就
研究方向
主要研究方向為DNA損傷修復與RNA質量控制。
發表論文
第一作者及共同第一作者論文
1. Shubo Zhao#; Jacqueline Cordes#; Karolina M. Caban; Maximilian J. Götz; Timur Mackens Kiani; Anthony J. Veltri; Niladri K. Sinha; Pedro Weickert; Selay Kaya; Graeme Hewitt; Danny D. Nedialkova; Thomas Fröhlich; Roland Beckmann; Allen R. Buskirk; Rachel Green; Julian Stingele; RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks, Molecular Cell, 2023, 83(23): 4290-4303 (IF:16)
2. Shubo Zhao; Anja Kieser; Hao-Yi Li; Hannah K Reinking; Pedro Weickert; Simon Euteneuer; Denitsa Yaneva; Aleida C Acampora; Maximilian J Götz; Regina Feederle; Julian Stingele; A ubiquitin switch controls autocatalytic inactivation of the DNA–protein crosslink repair protease SPRTN, Nucleic Acids Research, 2021, 49(2): 902-915 (IF:14.9)
其他作者論文
1. Christopher J Carnie#; Aleida C Acampora#; Aldo S Bader, Chimeg Erdenebat； Shubo Zhao; Elnatan Bitensky; Diana van den Heuvel; Avital Parnas; Vipul Gupta; Giuseppina D’Alessandro; Matylda Sczaniecka-Clift; Pedro Weickert; Fatih Aygenli; Maximilian J Götz; Jacqueline Cordes; Isabel Esain-Garcia; Larry Melidis; Annelotte P Wondergem; Simon Lam; Maria S Robles; Shankar Balasubramanian; Sheera Adar; Martijn S Luijsterburg; Stephen P Jackson*; Julian Stingele*; Transcription-coupled repair of DNA–protein cross-links depends on CSA and CSB, Nature Cell Biology, 2024 (IF:21.3)
2. Tingyu Wen; Shubo Zhao; Julian Stingele*; Jean-Luc Ravanat*; Marc M. Greenberg*; Quantification of Intracellular DNA–Protein Cross-Links with N7-Methyl-2’-Deoxyguanosine and Their Contribution to Cytotoxicity, Chemical Research in Toxicology, 2024 (IF:4.1)
3. Pedro Weickert; Hao-Yi Li; Maximilian J. Götz; Sophie Dürauer; Denitsa Yaneva; Shubo Zhao; Jacqueline Cordes; Aleida C. Acampora; Ignasi Forne; Axel Imhof; Julian Stingele; SPRTN patient variants cause global-genome DNA-protein crosslink repair defects, Nature Communications, 2023, 14(1) (IF:16.6)
4. Denitsa Yaneva#; Justin L. Sparks#; Maximilian Donsbach#; Shubo Zhao; Pedro Weickert; Rachel Bezalel-Buch; Julian Stingele*; Johannes C*. Walter; The FANCJ helicase unfolds DNA-protein crosslinks to promote their repair, Molecular Cell, 2023, 83(1): 43-56 (IF:16)
5. Hannah K. Reinking; Hyun-Seo Kang; Maximilian J. Götz; Hao-Yi Li; Anja Kieser; Shubo Zhao; Aleida C. Acampora; Pedro Weickert; Evelyn Fessler; Lucas T. Jae; Michael Sattler; Julian Stingele; DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease, Molecular Cell, 2020, 80(1): 102-113 (IF:16)
6. Yang Daowei#; Liang Yaoji#; Zhao Shubo; Ding Yan; Zhuang Qiuyu; Shi Qilin; Ai Tingting; Wu Suqin; Han Jiahuai; ZBP1 mediates interferon-induced necroptosis, Cellular & Molecular Immunology, 2019, 17(4): 356-368 (IF:24.1)
7. Zhang, Yingying#; Su, Sheng Sean#; Zhao, Shubo; Yang, Zhentao; Zhong, Chuan-Qi; Chen, Xin; Cai, Qixu; Yang, Zhang-Hua; Huang, Deli; Wu, Rui; Han, Jiahuai; RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome, Nature Communications, 2017, 8(1) (IF:16.6)
（#共同第一作者、*共同通訊作者）
榮譽表彰
被授予Summa cum laude德國博士最高榮譽以及慕尼黑大學化學與藥劑學學院Römer-Preise榮譽。
