崔清華

崔清華，女，雲南大學生命科學院教授。

基本介紹

• 中文名：崔清華
• 國籍：中國
• 畢業院校：中國科學院
• 學位/學歷：博士
• 專業方向：腫瘤的分子機制

人物經歷

1991-1995 河北大學環境生物學專業 學士

1998-1998 中科院昆明動物研究所動物學專業 碩士

1998-2001 中科院環境生態研究中心環境生化專業 博士

2002-2004 美國馬里蘭大學 分子遺傳學專業 博士後

2004-2009 美國范德堡大學癌症研究中心 研究科學家

2010-至今雲南大學 生化與分子生物學 教授

研究方向

本實驗室關注腫瘤中的相關調控機理，以細胞株及臨床病理樣品為材料，集中關注Bcl-2家族在細胞凋亡及自噬中的調控作用及與線粒體代謝的關係。

主要論文

1. Lei Ding, Huan Gu, Zhenwei Lan, Qingchun Lei, Wenxue Wang, Jie Lin, Min Yu and Qinghua Cui2019. Down-regulation of cyclooxygenase-1 stimulates mitochondrial apoptosis through NF-kB signaling pathway in Colorectal Cancer Cells. Oncology Reports, 41: 559-569.
2. Lei Ding, Zhenwei Lan, Xianhui Xiong, Hongshun Ao, Yingting Feng, Huan Gu, Min Yu, Qinghua Cui2018. The dual role of microRNAs in colorectal cancer progression. Int. J. Mol. Sci.. 19(9):2791
3. Kun YAO, Xu-feng FU, Xing DU, Yan LI, Shan-shan YANG, Min YU, Qing-hua CUI*. 2018. PGC-1α coordinates with Bcl-2 to control the cell cycle in U251 cells through reducing ROS. JZUS B, 19(6): 415-424
4. Da-Jian He, Ling Wang, Zhi-Bi Zhang, Kun Guo, Jing-Zheng Li, Xie-Chao He, Qing-Hua Cui*, Ping Zheng*. 2018. Maternal gene Ooep may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes. Zoo. Res. 39(6): 1-10.
5. Ran Wei, Qin Yang, Bing Han, Yan Li, Kun Yao, Zexi Chen, Jiaqi Zhou, Qinghua Cui. 2017. MicroRNA-375 inhibits colorectal cancer cells proliferation by downregulating JAK2/STAT3 and MAP3K8/ERK signaling pathways. Oncotarget DOI: 10.18632
6. Xing Du, Xufeng Fu, Kun Yao, zhenwei Lan, Hui Xu, Qinghua Cui*, Elizabeth Yang*. 2017. Bcl-2 delays cell cycle through mitochondrial ATP and ROS. Cell Cycle. 16(7): 707-713
7. Xu-feng Fu, Kun Yao, Xing Du, Yan Li, Xiu-yu Yang, Min Yu, Mei-zhang Li, Qing-hua Cui*. 2016. PGC-1a regulates the cell cycle through ATP and ROS in CH1 cells. JZUS B, 17 (2):136-146.
8. Wei Xu, Zexi Chen, Naeem Ahmed, Bing Han, Qinghua Cui* and Aizhong Liu*. 2016. Genome-Wide Identification, Evolutionary Analysis, and Stress Responses of the GRAS Gene Family in Castor Beans. Int. J. Mol. Sci. 17, 1004;
9. W. Wang, Y. Ye, J. Li, X. Li, X. Zhou, D. Tan, Y. Jin, E. Wu,Qinghua.Cuiand M. Wu. 2014. Lyn Regulates Cytotoxicity in Respiratory EpithelialCells Challenged by Cigarette Smoke Extracts.Curr. Mol. Med. 14,1-10
10. Wei Xu#,Qinghua Cui#, Fei Li, Aizhong Liu*. 2013. Transcriptome-wide identification and characterization of MicroRNAs from castor bean (Ricinus communis L.).PLOS ONE, 8 (7): e69995.
11. Qinghua Cui, Mayda Valentin, Yelena Janumyan, Elizabeth Yang. 2009. Bax-/- bak-/- cells exhibit p27Thr198 phosphorylation and autophagy.Autophagy5 (2): 263-264.
12. Yelena Janumyan#,Qinghua Cui#, Ling Yan, Courtney G. Sansam, Elizabeth Yang. 2008. Go function of BCL2 and BCL-xL requires BAX, BAK, and p27 phosphorylation, revealing a novel role of BAX and BAK in quiescence regulation.JBC, 283: 34108; 34120.
13. Ling Yan, Viviana A. Lavin, Leta R. Moser,Qinghua Cui, Cindy Kanies, and Elizabeth Yang. 2008. PP2A Regulates the Pro-apoptotic Activity of FOXO1. JBC 283: 7411; 7420.