余昊(華中科技大學物理學院教授)

余昊，男，博士，華中科技大學物理學院教授。

基本介紹

• 中文名：余昊
• 畢業院校：University of Alberta
• 學位/學歷：博士
• 職業：教師
• 專業方向：物理學
• 任職院校：華中科技大學
• 職稱：教授

研究方向

單分子生物物理

個人經歷

2007.9-2013.6University of Alberta＞物理學＞ 理學博士學位＞研究生(博士)畢業

2003.9-2007.7中國科學技術大學＞物理學＞ 理學學士學位＞本科(學士)

2017.6-至今華中科技大學 ＞物理學院＞教授

2014.2-2017.6JILA, University of Colorado Boulder ＞博士後

學術成果

論文：

[1]Yu, H., Heenan, P. R., Edwards, D. T., Uyetake, L., Perkins, T. T. Quantifying the Initial Unfolding of Bacteriorhodopsin Reveals Retinal Stabilization. Angew Chem Int Ed 131, 1724-1727 (2019).

[2]Heenan, P. R., Yu, H., Siewny, M. G. W., Perkins, T. T. Improved free-energy landscape reconstruction of bacteriorhodopsin highlights local variations in unfolding energy. The Journal of Chemical Physics , (2017).

[3]Yu, H., Dee, D. R., Liu, X., Brigley, A. M., Sosova, I., Woodside, M. T. Protein misfolding occurs by slow diffusion across multiple barriers in a rough energy landscape. Proc Natl Acad Sci U S A , (2015).

[4]Yu, H., Liu, X., Neupane, K., Gupta, A. N., Brigley, A. M., Solanki, A., Sosova, I., Woodside, M. T. Direct observation of multiple misfolding pathways in a single prion protein molecule. Proc Natl Acad Sci U S A (2012).

[5]Neupane, K., Ritchie, D. B., Yu, H., Foster, D. A., Wang, F., Woodside, M. T. Transition path times for nucleic Acid folding determined from energy-landscape analysis of single-molecule trajectories. Phys Rev Lett (2012).

[6]Yu, H., Siewny, M. G. W., Edwards, D. T., Sanders, A. W., Perkins, T. T. Hidden dynamics in the unfolding of individual bacteriorhodopsin proteins. Science (2017).

[7]Neupane, K., Foster, D. A., Dee, D. R. ,Yu, H., Wang, F., Woodside, M. T. Direct observation of transition paths during the folding of proteins and nucleic acids. Science (2016).

[8]Yu, H., Dee, D. R., Woodside, M. T. Single-molecule approaches to prion protein misfolding. Prion 7, (2013).

[9]Yu, H., Gupta, A. N., Liu, X., Neupane, K., Brigley, A. M., Sosova, I., Woodside, M. T. Energy landscape analysis of native folding of the prion protein yields the diffusion constant, transition path time, and rates. Proc Natl Acad Sci U S A 1, (2012).

[10]Neupane, K., Yu, H., Foster, D. A., Wang, F., Woodside, M. T. Single-molecule force spectroscopy of the add adenine riboswitch relates folding to regulatory mechanism. Nucleic Acids Res (2011).

科研項目

[1]高分辨力譜研究膜蛋白的錯誤摺疊

[2]SAM核糖開關摺疊動態與功能的單分子力譜研究。